摘要
目的探讨经乳晕切口手术治疗乳腺纤维瘤的临床效果及对患者血清血管内皮生长因子(VEGF)和基质金属蛋白酶-9(MMP-9)的影响。方法选取2017年2月至2018年1月就诊于该院共62例乳腺纤维瘤患者作为研究对象,根据手术治疗方法不同分为两组各31例。对照组患者采用传统手术切除治疗,试验组采用经乳晕切口手术治疗,观察和比较两组患者治疗效果。结果两组手术时间、术中出血量、瘢痕长度、切口愈合时间和住院时间与对照组比较,差异有统计学意义(P<0.05)。试验组术后MMP-9和VEGF水平均低于对照组,差异有统计学意义(P<0.05)。两组术后并发症发生率比较,差异有统计学意义(χ~2=13.425,P<0.05)。结论经乳晕切口手术治疗乳腺纤维瘤疗效显著,能减少患者手术应激反应,缩短术后恢复时间,并发症少,安全性高,有临床推广应用价值。
Objective To investigate the clinical effect of areola incision in the treatment of breast fibroma and its effect on serum vascular endothelial growth factor(VEGF)and matrix metalloproteinase-9(MMP-9).Methods A total of 62 patients with breast fibroma who were admitted to our hospital from February 2017 to January 2018 were enrolled in the study.They were divided into two groups according to different surgical treatment methods,31 cases each.The patients in the control group were treated with conventional surgical resection,and the experimental group was treated with areola incision.The therapeutic effects of the two groups were observed and compared.Results The operative time,intraoperative blood loss,scar length,incision healing time and hospital stay time of the two groups were significantly different from the control group(P<0.05).MMP-9 and VEGF levels in the experimental group were lower than those in the control group after surgery,and the differences were statistically significant(P<0.05).The incidence of postoperative complications between the two groups was statistically significant(χ~2=13.425,P <0.05).Conclusion The treatment of breast fibroma with areola incision is effective,which can reduce the surgical stress response,shorten the recovery time,less complications and high safetyI.thasthevalueofpopularization and application.
作者
王贤龙
WANG Xianlong(Department of Surgery,Shangnan County Hospital of Traditional Chinese Medicine,Shangluo,Shaanxi 726300,China)
出处
《检验医学与临床》
CAS
2020年第16期2328-2331,共4页
Laboratory Medicine and Clinic
