摘要
目的观察胃癌患者在根治术治疗后医院感染情况及其病原菌分布特点,分析患者医院感染可能的影响因素。方法采用回顾分析的方法,收集江阴市中医院和江阴市人民医院2013年2月-2019年4月接受根治术治疗的601例胃癌患者临床资料,观察患者医院感染发生情况,记录各主要病原菌分布与构成;设计一般资料调查表调查患者情况,将医院感染可能的影响因素纳入,经单因素与多因素分析找出胃癌根治术后医院感染的影响因素。结果 601例胃癌患者根治术后医院感染发生率为5.16%,检出病原菌共40株,革兰阴性菌占比高,检出少量真菌。经单因素及多因素分析结果显示,年龄、吸烟、合并糖尿病、营养状态、病理分期、白蛋白表达、住院时间等均可能是胃癌根治术后医院感染的危险因素(OR>1,P<0.05)。结论革兰阴性菌是胃癌根治术后医院感染主要病原菌,患者医院感染的发生主要受高龄、吸烟、合并糖尿病、营养状态差、病理分期高、白蛋白低表达、住院时间长等因素影响,这类患者应引起临床重视。
OBJECTIVE To observe the prevalence of postoperative nosocomial infection in gastric cancer patients undergoing radical surgery and distribution of pathogens and analyze the influencing factors for the nosocomial infection.METHODS By means of retrospective survey,the clinical data were collected from 601 gastric cancer patients who underwent radical surgery in Jiangyin Traditional Chinese Medicine Hospital and Jiangyin People’s Hospital from Feb 2013 to Apr 2019,the incidence of nosocomial infection was observed,the major species of pathogens were recorded,a questionnaire was designed for the patients’condition,involving the influencing factors for the nosocomial infection,and univariate analysis and multivariate analysis were performed for the influencing factors for the postoperative nosocomial infection.RESULTS Among the 601 gastric cancer patients who underwent the radical surgery,the incidence rate of postoperative nosocomial infection was 5.16%.Totally 40 strains of pathogens were isolated,among which the gram-negative were dominant.The results of univariate analysis and multivariate analysis showed that the age,smoking,complication with diabetes mellitus,nutrition status,pathological stage,expression of albumin and length of hospital stay might be the risk factors for the postoperative nosocomial infection in the gastric cancer patients(OR>1,P<0.05).CONCLUSION The gram-negative bacteria are dominant among the pathogens isolated from the gastric cancer patients with postoperative nosocomial infection.The major influencing factors for the nosocomial infection include the advanced age,smoking,complication with diabetes mellitus,poor nutrition status,high pathological stage,low expression of albumin and long length of hospital stay,which should be paid high attention to.
作者
茅伟达
凃威伟
孙筱虹
MAO Wei-da;TU Wei-wei;SUN Xiao hong(Jiangyin Traditional Chinese Medicine Hospital,Jiangyin,Jiangsu 214400,China;不详)
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2020年第14期2179-2183,共5页
Chinese Journal of Nosocomiology
关键词
胃癌根治术
医院感染
病原菌
影响因素
Gastrectomy
Nosocomial infection
Pathogen
Influencing factor
