摘要
慢性非萎缩性胃炎(CNG)属于常见病、多发病,严重影响患者的生活质量,如长期反复发作,有发展为慢性萎缩性胃炎甚至转化为胃癌的可能,因而,其防治措施尤为重要。目前,CNG发病机制尚不明确,症状无特异性,治疗以缓解症状及改善生活质量为主。西医治疗以质子泵抑制剂和胃黏膜保护剂使用频率最高,但常规西医治疗病程长、易反复,碍于西药长期使用的不良反应及患者长期治疗的依从性等因素,部分患者的问题未得到解决;中医以服用汤剂为主,辅以穴位贴敷等外用法,具有较好的安全性及疗效;临床上常以中西医结合法治疗CNG,疗效较西医更佳。本综述阐述CNG可能的发病机制及临床治疗现状,以期对广大患者、医护及科研人员提供借鉴价值。
Chronic non-atrophic gastritis(CNG)is a common and frequently-occurring diseases,which seriously affects the quality of life of patients.What′s more,long-term recurrent relapse may develop into chronic atrophic gastritis,even transform into gastric cancer.Therefore,the prevention and therapy of CNG is particularly important.At present,the pathogenesis of CNG is not clear,and the symptoms are not specific.The main treatment is relieving the symptoms and improving the quality of life.Proton pump inhibitors and gastric mucosal protective agents are used most frequently in Western medicine,but the problems of some patients have not been solved due to the adverse reactions of long-term use and the compliance with long-term treatment.Traditional Chinese medicine mainly takes decoction,supplemented with external application such as acupoint application,which has good safety and efficacy.The combination of traditional Chinese and Western medicine has better efficacy used to treat CNG in clinic than Western medicine.This review describes the possible pathogenesis and clinical treatment of CNG,aimed at providing reference value for patients,doctors,nurses and researchers.
作者
肖秋萍
李颖萌
刘文君
XIAO Qiu-ping;LI Ying-meng;LIU Wen-jun(Department of Research and Development,Jiangzhong Pharmaceutical Co.,Ltd.,Jiangxi Province,Nanchang 330096,China)
出处
《中国当代医药》
2020年第23期21-23,28,共4页
China Modern Medicine
基金
国家重点研发计划课题(2016YFD0400604-05)。
关键词
慢性非萎缩性胃炎
发病机制
治疗
中西医结合
Chronic non-atrophic gastritis
Pathogenesis
Therapy
The combination of traditional Chinese and Western medicine
