摘要
目的研究西安地区体检人群甲状腺激素水平及功能情况,探讨本地区甲状腺疾病防治策略。方法调取2018年1月1日至2018年12月31日在西安交通大学第二附属医院行健康体检人群的甲状腺激素测定数据,采用SAS统计学软件中的χ^2检验模块进行结果分析。结果纳入健康体检者4560例。亚临床甲减检出率最高(17.76%),其次为甲减(6.25%),甲亢居第三位(3.29%),亚临床甲亢发病率最低(0.79%)。亚临床甲减、甲减、亚临床甲亢的检出率女性高于或略高于男性,其中亚临床甲减(χ^2=37.77,P<0.0001)和亚临床甲亢(χ^2=10.28,P=0.0013)存在明显性别差异,而甲减和甲亢检出率无明显差异。总人群年龄分层结果显示亚临床甲减、甲亢、甲减检出率具有显著年龄差异,亚临床甲亢检出率无明显差异。结论西安地区健康体检人群亚临床甲功异常检出率显著高于临床甲功异常,以亚临床甲减、甲减、甲亢为主,而亚临床甲亢检出率最低;女性甲功异常检出率总体高于男性;不同年龄段检出率差异存在统计学意义。
Objective To investigate thyroid hormone level and function among physical examination people in Xi′an area and explore the prevention and control strategies of thyroid disease in this region.Methods Data of thyroid hormone assay was collected from healthy people who underwent physical examination in the Second Affiliated Hospital of Xi′an Jiaotong University from January 1,2018 to December 31,2018,and analyzed statistically.Results A total of 4,560 patients were included in the study cohort.The incidence of subclinical hypothyroidism was the highest(17.76%),followed successively by hypothyroidism(6.25%),hyperthyroidism(3.29%)and subclinical hyperthyroidism(0.79%).The incidences of subclinical hypothyroidism,hypothyroidism and subclinical hyperthyroidism in females were higher or slightly higher than those in males.There were significant gender differences between subclinical hypothyroidism(χ^2=37.77,P<0.0001)and subclinical hyperthyroidism(χ^2=10.28,P=0.0013),while no significant difference was observed between the incidence of subclinical hypothyroidism and hyperthyroidism.The age stratification of the total population showed that the incidences of subclinical hypothyroidism,hyperthyroidism and hypothyroidism had significant age differences,but subclinical hyperthyroidism had no significant difference.Conclusion The incidence of subclinical thyroidism in healthy people is significantly higher than clinical thyroidism in Xi′an area.The incidence of female thyroidism is generally higher than that of male and the incidence of different age groups has statistical differences.
作者
郑龙
豆晓杰
屈伟
李姗姗
何长武
宁宁
郑向红
ZHENG Long;DOU Xiaojie;QU Wei;LI Shanshan;HE Changwu;NING Ning;ZHENG Xianghong(Department of Nuclear Medicine, The Second Affiliation Hospital of Xi’an Jiaotong University, Xi’an 710004, China;Xi’anJiaotong University Health Science Center, Xi’an 710061, China)
出处
《标记免疫分析与临床》
CAS
2020年第8期1314-1316,1415,共4页
Labeled Immunoassays and Clinical Medicine
基金
陕西省社发攻关项目(编号:2015SF186)
西安交大二附院科研基金(编号:YJQN201628)。
关键词
甲状腺激素
体检人群
西安地区
Thyroid hormone
Physical examination people
Xi′an area
