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纤维支气管镜肺泡灌洗联合无创正压通气治疗慢性阻塞性肺疾病急性加重期合并Ⅱ型呼吸衰竭的临床疗效及安全性研究 被引量:6

Clinical Efficacy and Safety of Bronchoalveolar Lavage Combined with Noninvasive Positive Pressure Ventilation in the Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease Complicated with Type II Respiratory Failure
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摘要 目的:探究慢性阻塞性肺疾病急性加重期合并Ⅱ型呼吸衰竭患者采用纤维支气管镜肺泡灌洗与无创正压通气联合治疗的效果与安全性。方法:选取2017年9月~2019年9月本院收治的慢性阻塞性肺疾病急性加重期合并Ⅱ型呼吸衰竭患者,随机分为2组,对照组予以无创正压通气治疗,观察组在对照组前提下加用纤维支气管镜肺泡灌洗治疗,并对两组患者治疗效果、抗菌药静滴时间与住院时间及不良反应发生率进行比较。结果:对照组总有效率65.91%,明显低于观察组的93.19%(P<0.05);观察组抗菌药静滴时间与住院时间明显比对照组短(P<0.05);观察组不良反应发生率11.36%,与对照组的6.81%相比没有明显差异(P>0.05)。结论:慢性阻塞性肺疾病急性加重期合并Ⅱ型呼吸衰竭患者采用纤维支气管镜肺泡灌洗与无创正压通气联合治疗效果显著,安全性较好。 Objective:To explore the efficacy and safety of bronchoalveolar lavage combined with noninvasive positive pressure ventilation in patients with acute exacerbation of chronic obstructive pulmonary disease complicated with type II respiratory failure.Methods:From September 2017 to September 2019,patients with acute exacerbation of chronic obstructive pulmonary disease complicated with type II respiratory failure were selected and randomly divided into two groups.The treatment effect,intravenous drip time and hospitalization time of antibiotics and the incidence of adverse reactions were compared between the two groups.Results:The total effective rate of the control group was 65.91%,which was significantly lower than that of the experimental group(93.19%,P<0.05).The intravenous drip time and hospitalization time of antibiotics in experimental group were significantly shorter than those in control group(P<0.05).Conclusion:Patients with acute exacerbation of chronic obstructive pulmonary disease complicated with type II respiratory failure are treated by bronchoalveolar lavage combined with noninvasive positive pressure ventilation,and the safety is good.
作者 杨威 YANG Wei(Department of Internal Medicine,Shenyang Ninth People’s Hospital,Liaoning Shenyang 110024)
出处 《中国医疗器械信息》 2020年第15期94-95,共2页 China Medical Device Information
关键词 纤维支气管镜肺泡灌洗 无创正压通气 慢性阻塞性肺疾病急性加重期 Ⅱ型呼吸衰竭 治疗效果 noninvasive positive pressure ventilation acute exacerbation of chronic obstructive pulmonary disease type II respiratory failure treatment effect
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