摘要
目的:观察益气通络法联合rtPA对气虚血瘀型急性大脑中动脉(MCA)M1段闭塞脑梗死侧枝循环建立的影响。方法:选择确诊且符合静脉溶栓时间窗患者60例,按随机数字表法分成两组各30例,对照组予rtPA静脉溶栓治疗,治疗组在rtPA静脉溶栓基础上,予补阳还五汤治疗,连服14天,比较两组患者的疗效。结果:治疗后7天、14天两组NIHSS、mRS评分较治疗前均有明显降低,且治疗组优于对照组(P﹤0.05)。治疗组总有效率高于对照组(P﹤0.05)。MCA M1段闭塞同侧ACA、PCA平均血流速度较治疗前均有明显增加(P﹤0.05),且组间比较治疗组优于对照组,有统计学差异(P﹤0.05)。结论:补阳还五汤益气通络联合rtPA能提高气虚血瘀型急性大脑中动脉(MCA)M1段闭塞脑梗死的疗效,且有利于侧枝循环的建立,明显改善预后。
Objective:To observe the clinical effect of Yiqi Tongluo therapy and rtPA on acute middle cerebral artery(MCA)M1 segment occlusion-caused cerebral infarction with qi-deficiency and blood-stasis syndrome.Methods:60 cases of selected patients,who were diagnosises as MCA M1 segment occlusion-caused acute cerebral infarction in our hospital and met the time window of intravenous thrombolysis,were randomly divided into two groups,30 cases in each group.The control group was treated by rtPA intravenous thrombolysis;while the treatment group was treated by Yiqi Tongluo therapy(selected recipe was Buyang Huanwu decoction)on the basis of control group,continuously orally for 14 days.Results:On the 7th d.and the 14th d.the scores of NIHSS and mRS in both groups were significantly lower than that before treatment,and the treatment group was better than the control group(P<0.05).The total effective rate of treatment group was higher than that of control group.Compared with before treatment,mean flow velocity in ACA and PCA of same lateral of MCA M1 segment occlusion was significantly increased(P<0.05),and the treatment group was better than the control group compared between two groups,and there was a statistical difference(P<0.05).Conclusion:Buyang Huanwu decoction for replenishing qi to dredge collaterals combined with rtPA is effective on acute middle cerebral artery(MCA)M1 segment occlusion-caused cerebral infarction with qideficiency and blood-stasis syndrome,which is advantageous to establishment of collateral circulation,and can improve the prognosis.
作者
张瑞杰
ZHANG Rui-jie(Heze Hospital of Traditional Chinese Medicine,Shandong Province,Heze274000,China)
出处
《山西中医》
2020年第9期23-25,共3页
Shanxi Journal of Traditional Chinese Medicine
基金
山东省中医药科技发展计划项目(编号:2019-0934)。
关键词
急性大脑中动脉(MCA)M1段闭塞脑梗死
气虚血瘀
益气通络
RTPA
大脑中动脉
侧枝循环
中西医结合疗法
acute middle cerebral artery(MCA)M1 segment occlusion-caused cerebral infarction
qi-deficiency and blood-stasis syndrome
Yiqi Tongluo therapy
rtPA
middle cerebral artery
collateral circulation
