摘要
目的研究多囊卵巢综合征(PCOS)患者用阿司匹林+来曲唑治疗效果。方法研究时段2019年1—7月,研究对象是方便选取该院门诊接收的66例PCOS患者,采纳门诊就诊先后顺序划分观察组(阿司匹林+来曲唑)与对照组(克罗米芬)各33例,比较两组治疗效果。结果治疗前比较两组血清激素水平差异无统计学意义(P>0.05);治疗后与对照组比较,观察组E2、LH及FSH指标低,P指标高;优势卵泡数目多,子宫内膜增生厚度及宫颈黏膜评分低;观察组有效率(96.97%)高于对照组81.22%;观察组妊娠率(87.88%)及排卵率(90.91%)高于对照组63.43%及69.70%,观察组流产率(6.06%)低于对照组24.24%,差异有统计学意义(χ^2=3.995、5.280、4.694、4.243,P<0.05)。结论阿司匹林+来曲唑治疗PCOS患者能提高整体疗效及妊娠成功率。
Objective To study the effect of aspirin+letrozole in patients with polycystic ovary syndrome(PCOS).Methods The study period was from January 2019 to July 2019.The study subjects were 66 PCOS patients received in the outpatient clinic.The outpatient visits were divided into observation group(aspirin+letrozole)and control group(clomiphene),33 cases in each group,compare the treatment effect of the two groups.Results Before treatment,there was no statistically significant difference in serum hormone levels between the two groups(P>0.05);after treatment,compared with the control group,the observation group had low E2,LH and FSH indexes,and high P indexes;the number of dominant follicles was large,the thickness of endometrial hyperplasia and cervical mucosa score was low;the effective rate of the observation group(96.97%)was higher than that of the control group 81.82%;the pregnancy rate(87.88%)and ovulation rate(90.91%)of the observation group were higher than the control group 63.64%and 69.70%.The abortion rate in the observation group was 6.06%,lower than the control group 24.24%,the difference was statistically significant(χ^2=3.995,5.280,4.694,4.243,P<0.05).Conclusion Aspirin+letrozole in the treatment of PCOS patients can improve the overall efficacy and pregnancy success rate.
作者
赵瑞华
ZHAO Rui-hua(Department of Obstetrics and Gynecology,Southwest Hospital of Shandong,Liaocheng,Shandong Province,252300 China)
出处
《中外医疗》
2020年第19期97-99,共3页
China & Foreign Medical Treatment
