摘要
人工关节置换术后假体周围感染(PJI)是接受人工关节置换术患者常见的术后并发症之一。在对患者进行人工关节置换术后,导致其发生PJI的常见致病菌多为革兰阴性菌,由真菌引起的感染极为少见。目前,临床上对于接受人工关节置换术后并发真菌感染的患者尚无特效的治疗手段。伏立康唑是一种广谱的三唑类抗真菌药。本文主要是总结用关节腔内注射伏立康唑疗法对1例接受人工膝关节置换术后并发真菌感染患者进行治疗的效果及经验。
Periprosthetic infection(PJI)after joint replacement is one of the common postoperative complications in patients undergoing joint replacement.After artificial joint replacement,most of the common pathogenic bacteria causing PJI in patients were gram-negative bacteria,and fungal infections were very rare.At present,there is no effective treatment for patients with fungal infection after joint replacement.Voriconazole is a broad-spectrum triazole antifungal drug.In this paper,we summarize the therapeutic effect and experience of one patient with fungal infection after arthroplasty with voriconazole.
作者
曾少方
黄碧瑜
劳海燕
Zeng Shaofang;Huang Biyu;Luo Haiyan(Wuhua County People’s Hospital,Wuhua 514400,China;Guangdong Provincial People’s Hospital/Department of Pharmacy,Guangdong Academy of Medical Sciences,Guangzhou 510080,China)
关键词
伏立康唑
人工膝关节置换术
真菌感染
Voriconazole
Artificial knee replacement
Fungal infection
