摘要
文章探讨了抗生素的使用和细菌耐药性情况。对125名感染患者进行抗生素类型、使用情况以及各种抗生素的耐药性评估。抗生素使用率为96.0%,头孢菌素比例最高(96.7%)。抗生素的预平均使用时间(23.21±2.52)d,联合用药率为53.3%。革兰阴性和阳性菌的耐药性主要体现在青霉素类和头孢类抗生素中。医生应充分整合细菌的耐药性,并适当使用抗生素以确保药物安全性。
This article investigated the use of antibiotics and bacterial resistance.125 infected patients were evaluated of antibiotic type,use and antibiotic resistance.The utilization rate of antibiotics was 96.0%,and the cephalosporin was the highest(96.7%).The average pre-administration time of antibiotics was(23.21±2.52)days,and the combined administration rate was 53.3%.The resistance of gram-negative and gram-positive bacteria was mainly reflected in penicillin and cephalosporin antibiotics.Doctors should fully integrate the drug resistance of bacteria,and appropriately use antibiotics to ensure drug safety.
作者
张伟亮
米燕
侯生举
王娟
ZHANG Weiliang;MI Yan;HOU Shengju;WANG Juan(North China Pharmaceutical Co.,Ltd.,Shijiazhuang 052165,China;Wuji County People's Hospital,Shijjazhuang 052460,China;Shijiazhuang Chemical Fiber Technology Innovation Center,Shijazhuang University,Shijiazhuang 050035,China)
基金
河北省重点研发计划项目(19211203D)
石家庄市化学纤维技术创新中心建设项目(198190167A)
石家庄市科技型中小企业技术创新基金(19SCX05002)。
关键词
抗生素应用
细菌耐药性
药物敏感试验
antibiotic application
bacterial resistance
drug sensitivity test
