摘要
本研究建立了食品接触硅胶制品中9种芳香烃(甲苯、乙苯、邻/间/对/二甲苯、1,2,4,5-四甲苯、萘、1-甲基萘、2-甲基萘)的固相微萃取-气相色谱串联质谱分析方法,并对31种奶嘴和32种模具中的9种芳香烃含量进行了测定。假设制品中9种芳香烃100%迁移至食品,通过@RISK风险评估软件建立的简单分布评估模型,计算模具和奶嘴中芳香烃的估计每日摄入量;结合国内外限量要求,对其进行暴露评估及风险评价。结果表明,所建方法高效、灵敏、可靠,9种芳香烃的检出限在6.30×10^-3~0.06 ng/mL范围,平均方法回收率为98.24%~110.23%。9种芳香烃在31种奶嘴和32种模具中的平均含量分别在6.91~129.79 ng/g和50.73~1376.78 ng/dm^2范围。在假设100%迁移的情况下,9种芳香烃在奶嘴和模具中的平均估计每日摄入量分别为1.06~21.63 ng/kg bw和0.47~12.63 ng/kg bw,均低于欧盟规定的甲苯和乙苯的日允许摄入量,提示其迁移所可能导致的安全风险较小。
In this study,a solid phase micro-extraction coupled with gas chromatography tandem mass spectrometry(SPME-GC-MS/MS)method was established for the analysis of 9 aromatics(toluene,ethylbenzene,o/p/m-xylene,1,2,4,5-tetramethylbenzene,naphthalene,1-methylnaphthalene,2-methylnaphthalene)in food contact silicone products.The contents of 9 aromatics in 31 nipples and 32 molds were determined and analysis.Suppose that 9 aromatics could completely to food,a simple distribution assessment model was established by the@RISK to calculate the estimated daily intake of 9 aromatics in the molds and nipples.Finally,through the exposure assessment combined with the existing regulations at home and abroad,the preliminary safety assessment was carried out.The results indicated that the analysis method was efficient,sensitive and reliable.The detection limit of 9 aromatics ranged from 6.30×10^-3 to 0.06 ng/mL,and the average recovery rate from 98.24%to 110.23%.The average content of 9 aromatics was 6.91-129.79 ng/g in 31 nipples and 50.73-1376.78 ng/dm^2 in 32 molds,respectively.In the case of hypothetical extreme migration,the estimated daily intake of 9 aromatics was 1.06-21.63 ng/kg bw in 31 nipples and 0.47-12.63 ng/kg bw in 32 molds,which were lower than the EU limits.The results indicated that the migration of 9 aromatics may result in less safety risks.
作者
王文娟
蔡小芳
袁航
戚冬雷
封棣
Wang Wenjuan;Cai Xiaofang;Yuan Hang;Qi Donglei;Feng Di(School of Light Industry,Beijing Technology and Business University,Beijing 100048)
出处
《中国食品学报》
EI
CAS
CSCD
北大核心
2020年第11期208-217,共10页
Journal of Chinese Institute Of Food Science and Technology
基金
国家自然科学基金项目(31871722)。
关键词
食品接触硅橡胶材料
芳香烃
检测
固相微萃取
气相色谱串联质谱
安全风险评价
food contact silicone rubber material
aromatic hydrocarbon
detection
solid phase micro-extraction
gas chromatography tandem mass spectrometry
safety risk evaluation
