摘要
长链非编码RNA(lncRNA)主要分布在胞核和胞质中,主要调控翻译过程以及蛋白质的靶向运输,比其他非编码RNA种类更多,功能更为复杂。近年来发现lncRNA可能在脑卒中的病理过程中发挥着重要作用。本文对lncRNA调控脑卒中后血管新生方面的研究进展进行综述,以明确lncRNA在缺血性脑卒中血管新生中的作用。
Long non-coding RNA(lncRNA)is mainly distributed in the nucleus and cytoplasm.It mainly regulates the translation process and targeted transport of proteins.It has more types and more complex functions than other non-coding RNAs.Recent studies have shown that lncRNA may play an important role in the pathological process of stroke.This article reviews the research progress of the molecular biological mechanism of lncRNA regulating angiogenesis after stroke to clarify the role of lncRNA in angiogenesis of ischemic stroke.
作者
李潇
周爽
赵琛
LI Xiao;ZHOU Shuang;ZHAO Chen(Acupuncture and Tuina College of Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China)
出处
《天津医药》
CAS
北大核心
2020年第12期1236-1239,共4页
Tianjin Medical Journal
基金
国家自然科学基金资助项目(81874505,81574059)。
