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宫腔镜联合垂体后叶素治疗剖宫产切口妊娠的临床价值

Value of Hysteroscopy Combined with Pituitrin for Cesarean Section Incision Pregnancy
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摘要 目的探讨宫腔镜联合垂体后叶素治疗剖宫产切口妊娠的临床价值。方法回顾性分析2014年7月至2018年5月本院收治的剖宫产术后切口妊娠患者25例,按时随机数字表法分为两组,均为25例。对照组实施双侧子宫动脉介入栓塞并清宫治疗,观察组则实施垂体后叶素注射联合宫腔镜下清宫治疗,对所有入组者随访1年,比较两组手术相关指标,干预前后两组炎性因子相关指标,术后功能正常妊娠情况。结果观察组手术出血少于对照组,血β-HCG正常时间和术后月经复潮时间短于对照组(P<0.05);干预后两组hs-CRP水平显著下降,且观察组明显低于对照组(P<0.05);观察组宫内正常妊娠比例达到37.5%,显著高于对照组的5.0%(P<0.05)。结论针对剖宫产术后切口妊娠实施垂体后叶素联合宫腔镜,操作简单,对患者内分泌影响小,显著减轻炎性反应,促进术后再妊娠。 Objective To explore the clinical value of hysteroscopy combined with pituitrin in the treatment of cesarean section incision pregnancy.Methods Retrospective analysis of 50 cases with cesarean section incision pregnancy admitted to our hospital from July 2014 to May 2018 were selected and randomly divided into two groups with 40 cases in each group.The control group was treated with bilateral uterine artery interventional embolization and curettage,while the observation group was treated with pituitrin injection combined with hysteroscopic curettage.All the participants were followed up for 1 year.Then the operation-related indexes in the two groups were compared,the inflammatory factor-related indexes in the two groups before and after the intervention,and the pregnancy with normal postoperative function were compared.Results The operative hemorrhage in the observation group was less than that control group,the normal time of bloodβ-HCG and the time of menstruation recurrence after operation were shorter than control group(P<0.05).The levels of inflammatory factors hs-CRP in the observation group after intervention were significantly lower than control group before and after intervention(P<0.05).The normal pregnancy rate in the observation group reached 37.5%,it was significantly higher than control group(P<0.05).Conclusion The combination of pituitrin and hysteroscope for cesarean section incision pregnancy is simple to operate,it has little influence on endocrine of patients,so it can significantly reduce inflammatory reaction and promote post-operation pregnancy.
作者 潘晓萌 邓新 孙远旭 PAN Xiaomeng;DENG Xin;SUN Yuanxu(Dalian Maternal and Child Health Hospital,Dalian 116021,China)
出处 《中国医药指南》 2020年第31期96-97,共2页 Guide of China Medicine
关键词 剖宫产 宫腔镜 垂体后叶素 切口妊娠 Cesarean section Hysteroscopy Pituitrin Incisional pregnancy
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