摘要
目的调查广东省妇幼保健院就诊的PCOS患者焦虑及抑郁的发病现状,分析发病的危险因素,从而为临床治疗提供指导。方法选取2017年8月至2019年2月在广东省妇幼保健院妇科内分泌门诊就诊的PCOS患者作为研究对象,使用GAD⁃7、PHQ⁃9症状自评量表以及睡眠问卷对患者精神状态及睡眠质量进行评估,并采集患者的一般临床资料及血液生化指标进行分析。结果262例入组患者中,有80例(30.5%)出现焦虑症状,76例(29.0%)出现抑郁症状。睡眠障碍(OR=3.544,95%CI:1.641~7.652)是PCOS患者抑郁症状出现的危险因素。睡眠障碍(OR=3.938,95%CI:1.804~8.597)与WHR异常(OR=94.904,95%CI:1.328~6780.675)是PCOS患者焦虑症状出现的危险因素。结论PCOS患者容易出现焦虑和抑郁情绪,睡眠障碍是引起PCOS患者抑郁及焦虑出现的危险因素;腰臀比异常是PCOS患者焦虑症状出现的危险因素。临床医生应重视PCOS患者的精神心理健康。
Objective To investigate the incidence of anxiety and depression in PCOS patients in Guang⁃dong Women and Children′s Hospital and analyze the risk factors of the disease so as to provide guidance for clinical treatment.Methods PCOS patients who were admitted to the Guangdong Women and Children Hospital from August 2017 to February 2019 were selected as subjects for the survey using GAD⁃7,PHQ⁃9 Symptom Check⁃list and Sleep Questionnaire.The patient′s mental state and sleep quality were assessed,and the patient′s general clinical data and blood biochemical indicators were collected for analysis.Results Of the 262 patients enrolled,80(30.5%)had anxiety disorder and 76(29.0%)had depressive disorder.Sleep disorders(OR=3.544,95%CI:1.641~7.652)was an independent risk factor for the depression in patients with PCOS.Sleep disorders(OR=3.938,95%CI:1.804~8.597)and WHR(OR=94.904,95%CI:1.328~6780.675)were independent risk factors for anxiety in patients with PCOS.Conclusion Patients with PCOS are prone to comorbid anxiety and depression.Sleep disorders is an independent risk factor for the onset of depression and anxiety in patients with PCOS.Waist⁃to⁃hip ratio is an independent risk factor for the onset of anxiety in patients with PCOS.Clinicians should pay attention to the screening of anxiety and depression among PCOS patients.
作者
谭秋晓
张红梅
李洁明
陈志静
张小伟
李荔
TAN Qiuxiao;ZHANG Hongmei;LI Jieming;CHEN Zhijing;ZHANG Xiaowei;LI Li(Department of Obstetrics and Gynecology,Guangdong Women and Children Hospital,Guangzhou 511442,China;The Seventh Affiliated Hospital,SunYat-sen University,Shenzhen 518107,China;不详)
出处
《实用医学杂志》
CAS
北大核心
2020年第23期3288-3292,共5页
The Journal of Practical Medicine
基金
广东省中医药局重点专项(编号:20184005)
广东省科技发展专项基金(编号:2017ZC0378)
广州市科技计划科学研究专项(编号:201904010458)。
