摘要
2020年的诺贝尔化学奖颁给了两位研究CRISPR/Cas9的科学家,以表彰她们对新一代基因编辑技术开发及分子机制研究所做出的贡献。CRISPR/Cas9基因编辑技术一经诞生就被视为21世纪最为重要的生物发现之一。由于其稳定高效,CRISPR/Cas9技术已经成为基因组编辑的强大工具,在生命科学的各个领域都展现出广阔的应用前景,并且也为疾病的临床治疗提供了新策略。文章回顾了两位科学家对CRISPR/Cas9基因编辑系统开发的重要贡献,同时也对基因编辑技术的发展及应用进行了简单介绍。
The 2020 Nobel Prize in Chemistry was awarded to two scientists for their discoveries of CRISPR/Cas9 gene editing and its molecular mechanisms.The CRISPR/Cas9 gene editing technology is regarded as one of the most important biological discoveries in the 21st century.Their discovery has led to widespread applications of the CRISPR-Cas9 system as a powerful and versatile tool in genome editing.Here,the development and application of the CRISPR/Cas9 gene editing technology and the contributions of scientists are introduced.
作者
蒋艳红
吴宇轩
JIANG Yanhong;WU Yuxuan(Shanghai Key Laboratory of Regulatory Biology,Institute of Biomedical Sciences and School of Life Sciences,East China Normal University,Shanghai 200241,China)
出处
《自然杂志》
2020年第6期456-462,共7页
Chinese Journal of Nature
