摘要
目的采用星点设计-效应面法优选巫山淫羊藿油炙炮制工艺。方法选取炮制温度、炮制时间、占锅体积作为主要考察因素,以朝藿定A、朝藿定B、淫羊藿苷、朝藿定C的含量作为考察指标,采用星点设计-效应面法优选巫山淫羊藿的炮制工艺。结果炮制温度115℃,炮制时间10 min,占锅体积25%(约12.5 g)时的工艺最佳。结论采用星点设计-效应面法优选所得的巫山淫羊藿油炙炮制工艺合理。
Objective To optimize the processing technique for Epimedii Wushanensis Folium by central composite design (CCD)-response surface methodology (RSM).Methods The processing temperature,processing time and in-pot Epimedii Wushanensis Folium volume were selected as the main factors for the study.The content of epimedin A,epimedin B,icariin and epimedin C were used as indicators,and CCD-RSM was adopted to optimize the processing technique for Epimedii Wushanensis Folium.Results The optimal processing condition was 115℃for 10 minutes,with the in-pat volume at 25% (weight at 12.5 g).Conclusion The optimal processing technique for Epimedii Wushanensis Folium is reasonable established by CCD-RSM.
作者
苏菲菲
杨珍
窦志英
常艳旭
何俊
王晖
庞树朝
SU Fei-fei;YANG Zhen;DOU Zhi-ying;CHANG Yan-xu;HE Jun;WANG Hui;PANG Shu-chao(Tianjin Key Laboratory of Chinese Medicine Pharmacology,College of Chinese Materia Medica,Tianjin University of Traditional Chinese Medicine,Tianjin 300193;College of Chinese Materia Medica,Tianjin University of Traditional Chinese Medicine,Tianjin 300193;Tianjin State Key Laboratory of Modern Chinese Medicine,Tianjin University of Traditional Chinese Medicine,Tianjin 300193;Tianjin Key Laboratory of Phytochemistry and Pharmaceutical Analysis,Tianjin University of Traditional Chinese Medicine,Tianjin 300193;First Teaching Hospital of Tianjin University of Traditional Chinese Medicine,Tianjin 300193)
出处
《中南药学》
CAS
2020年第12期1962-1965,共4页
Central South Pharmacy
基金
国家自然科学基金(No.81703702
No.21405113)。
关键词
巫山淫羊藿
星点设计-效应面法
炮制工艺
Epimedii Wushanensis Folium
central composite design-response surface methodology
process technology
