摘要
如何改善移植肾的长期预后和解决供肾短缺仍是困扰临床医师的两大难题,其中缺血-再灌注损伤(IRI)、排斥反应、感染、免疫抑制治疗是肾移植研究领域的重要问题。因此,加强肾移植领域文献学习,了解移植肾相关疾病的本质及国际前沿研究热点,有助于临床进一步改善移植肾功能和延长移植肾的存活时间。本文就2020年第3季度肾移植领域的研究热点、最新进展并结合第12期岭南读书会的会议纪要作一文献解读,并从IRI、排斥反应和感染3个方面进行综述。
How to improve the long-term prognosis of transplant kidney and solve the shortage of donor kidney are still two major problems that plague clinicians.Among them,ischemia-reperfusion injury(IRI),rejection,infection,and immunosuppressive therapy are important issues in the research field of renal transplantation.Therefore,strengthening the literature study in the field of renal transplantation and understanding the nature of transplant kidney related diseases and international frontier research hotspots,help to further improve the function and prolong the survival time of the transplant kidney in clinic.This article interpreted literatures on the research hotspots and new progress in the field of renal transplantation in the third quarter of 2020,combined with the meeting minutes of the 12th Lingnan Reading Club,and reviewed from the three aspects of IRI,rejection and infection.
作者
马茂林
石炳毅
孙启全
Ma Maolin;Shi Bingyi;Sun Qiquan(Department of Renal Transplantation,the Third Affiliated Hospital of Sun Yat-sen University,Guangzhou 510630,China)
出处
《器官移植》
CAS
CSCD
北大核心
2021年第1期37-42,共6页
Organ Transplantation
基金
国家自然科学基金(81770753、81970650)
国家重点研发计划课题(2018YFA0108804)。
