摘要
目的研究2019年我院临床分离铜绿假单胞菌的分布及耐药性,为临床合理使用抗菌药物提供参考。方法收集我院2019年临床分离的422株铜绿假单胞菌,对其标本来源分布,科室分布和耐药性进行分析。结果共分离出422株铜绿假单胞菌。痰液、脓液、肺泡灌洗液分别占71.1%、7.3%、5.2%;科室分布以重症监护室最多(19.9%),其后依次为呼吸内科(17.1%)、胸外科病房(8.5%)。2019年铜绿假单胞菌对阿米卡星耐药率最低,为0.2%;对多粘菌素、妥布霉素等药物耐药率较低,分别为0.3%和1.7%;而对替卡西林/克拉维酸的耐药率最高,为17.7%。结论应加强细菌耐药监测,采取有效措施控制耐药菌株传播。
Objective To explore the distribution and drug resistance of pseudomonas aeruginosa in our hospital in 2019,and to provide reference for rational use of antibiotics in clinics.Methods Four hundred and twenty-two Strains of pseudomonas aeruginosa were collected in our hospital in 2019,and the specimen source,department distribution and the drug resistance were analyzed.Results Totally 422 strains of pseudomonas aeruginosa were isolated.The primary source included sputum(71.1%),fester(7.3%),alveolar lavage fluid(5.2%);pseudomonas aeruginosa was mainly detected from ICU(19.9%),followed by department of respiratory medicine(17.1%)and department of thoracic surgery ward(8.5%).In 2019 the drug resistance rates of pseudomonas aeruginosa against amikacin was the lowest(0.2%);the pseudomonas aeruginosa had a lower resistance against polymyxin(0.3%)and tobramycin(1.7%),but it had higher resistance rate against ticacillin/clavulanic acid.Conclusion Bacterial drug resistance monitoring should be strengthened,and effective measures should be taken to control the spread of drug-resistant strains.
作者
赵红梅
刘圣勋
孙景云
安新业
纪冰
彭新国
ZHAO Hongmei;LIU Shengxun;SUN Jingyun;AN Xinye;JI Bing;PENG Xinguo(Department of Laboratory Medicine,Binzhou Medical University Hospital,Binzhou 256603,Shandong,P.R.China)
出处
《滨州医学院学报》
2020年第6期423-425,共3页
Journal of Binzhou Medical University
基金
滨州医学院科技计划(BY2018KJ23)
山东省医药卫生科技发展计划(2017WS372)。
关键词
铜绿假单胞菌
耐药
抗生素
pseudomonas aeruginosa
drug resisitance
antimicrobial
