摘要
糖尿病视网膜病变及糖尿病肾病是糖尿病的两种慢性微血管并发症,二者有相似的病理机制,同时也存在差异。临床上诊断糖尿病肾病的金标准是肾组织活检病理,但由于其有创性和技术难度使患者的接受度和技术普及度受到限制,寻求可靠的无创诊断方法是解决这一问题的关键。基于彩色眼底照相技术诊断糖尿病视网膜病变为无创诊断糖尿病肾病提供了可能。越来越多的研究表明,结合糖尿病视网膜病变及其他临床指标辅助诊断糖尿病肾病具有较高的可信度及可行性。该文就糖尿病视网膜病变对糖尿病肾病的影响及其诊断价值进行综述。
Diabetic retinopathy and diabetic nephropathy are two chronic microvascular complications of diabetes.Some studies have shown that the both microvascular complications possess similar pathological mechanisms and some differences.The gold standard for clinical diagnosis of diabetic nephropathy is the pathology of renal biopsy.Of which,however,the acceptance of patients and the popularity of the technology have been limited for its invasiveness and technical difficulty.Therefore,the key to solve this problem is to seek a reliable noninvasive diagnosis method.The diabetic retinopathy diagnosed by color fundus photography opens the possibility of noninvasive diagnosis of diabetic nephropathy.A growing number of studies have shown that it has a high degree of credibility and feasibility to combine diabetic retinopathy and other clinical indicators to assist in diagnosing diabetic nephropathy.The effects and diagnostic value of diabetic retinopathy on diabetic nephropathy,therefore,have been reviewed in present article.
作者
蒋双双
陈小鸟
董哲毅
王倩
陈香美
Jiang Shuang-Shuang;Chen Xiao-Niao;Dong Zhe-Yi;Wang Qian;Chen Xiang-Mei(School of Clinical Medicine,Guangdong Pharmaceutical University,Guangzhou 510006,China;Department of Nephrology,Chinese PLA General Hospital/Chinese PLA Institute of Nephrology/State Key Laboratory of Kidney Diseases/National Clinical Research Center for Chronic Kidney Diseases/Beijing Key Laboratory of Kidney Diseases Research,Beijing 100853,China;Beijing Tongren Eye Center,Beijing Tongren Hospital,Capital Medical University,Beijing 100730,China)
出处
《解放军医学杂志》
CAS
CSCD
北大核心
2021年第1期64-70,共7页
Medical Journal of Chinese People's Liberation Army
基金
国家重点研发计划项目(2016YFC1305503)
国家自然科学基金青年基金(81700629)
北京市科技计划课题(D171100002817002)
解放军总医院大数据项目(2019MBD-053)。
