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替罗非班给药时机对急性非ST段抬高型心肌梗死经皮冠状动脉介入治疗临床效果影响 被引量:10

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摘要 目的探讨替罗非班给药时机对急性非ST段抬高型心肌梗死经皮冠状动脉介入治疗(PCI)临床效果的影响。方法选取某医院自2015年9月至2018年8月收治的74例急性非ST段抬高型心肌梗死患者为研究对象,所有患者均行PCI。根据替罗非班给药时机不同,将患者分入术前用药组(PCI前6 h内给药)和术后用药组(PCI后即刻给药),每组各37例。比较两组患者治疗前后的肌钙蛋白、肌酸激酶、肌酸激酶同功酶、乳酸脱氢酶、血小板计数的差值,以及心肌梗死溶栓(TIMI)分级。结果术前用药组和术后用药组的TIMI分级、乳酸脱氢酶差值、血小板计数差值比较,差异无统计学意义(P>0.05)。术前用药组的肌钙蛋白差值、肌酸激酶差值、肌酸激酶同功酶差值均大于术后用药组,差异有统计学意义(P<0.05)。结论对于行PCI的急性非ST段抬高型心肌梗死患者,PCI前给予替罗非班在改善肌钙蛋白、肌酸激酶、肌酸激酶同功酶方面的临床效果优于PCI后给药。
作者 李泽 陈立新
出处 《临床军医杂志》 CAS 2021年第1期97-98,共2页 Clinical Journal of Medical Officers
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