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子宫内膜容受性与体外受精/卵胞浆内单精子注射-胚胎移植患者妊娠结局的关系 被引量:8

The relationship between endometrial receptivity and pregnancy outcome in patients undergoing in vitro fertilization/intracytoplasmic sperm injection-embryo transfer
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摘要 目的探讨移植当日体外受精/卵胞浆内单精子注射-胚胎移植(IVF/ICSI-ET)患者子宫内膜容受性对妊娠结局的影响。方法选择2018年2月~2019年2月在我院接受IVF/ICSI-ET辅助生殖技术的100例不孕患者,在ET日行经阴道三维超声检查,根据最终妊娠结局,分为妊娠组(51例)与非妊娠组(49例),对比两组超声参数。结果妊娠组患者子宫内膜厚度高于非妊娠组(P=0.027),两组子宫内膜容积、形态比较,差异无统计学意义(P=0.673,0.687)。妊娠组患者子宫内膜血流参数PI、RI、S/D值均低于非妊娠组(P<0.05),两组患者血流分型比较,差异有统计学意义(P<0.05)。妊娠组患者子宫内膜及内膜下血流参数VI、FI、VFI均高于非妊娠组(P<0.05)。结论ET日行经阴道三维超声检测可预测子宫内膜容受性,评估IVF/ICSI-ET妊娠结局。 Objective:To investigate the effect of endometrial receptivity on pregnancy outcome in IVF/ICSI-ET patients on the day of transplantation.Methods:A total of 100 infertile patients who received IVF/ICSI-ET assisted reproduction technology in our hospital from February 2018 to February 2019 were selected and underwent transvaginal 3D ultrasound examination on the day of ET.According to the final pregnancy outcome,they were divided into the pregnancy group(51 cases)and non-pregnancy group(49 cases).The ultrasound parameters of the two groups were compared.Results:Endometrial thickness of the pregnant group was higher than that of the non-pregnant group(P=0.027),and there was no statistically significant difference in endometrial volume and morphology between the two groups(P=0.673,0.687).The endometrial blood flow parameters PI,RI and S/D in the pregnancy group were lower than those in the non-pregnancy group(P<0.05).The difference in blood flow typing between the two groups was statistically significant(P<0.05).Endometrial and subintimal blood flow parameters VI,FI and VFI were higher in the pregnancy group than in the non-pregnancy group(P<0.05).Conclusion:Daily transvaginal three-dimensional ultrasonography of endometrial receptivity is valuable for predicting pregnancy outcome.
作者 王彬 彭宇洪 梁见弟 陈惠南 WANG Bin;PENG Yu-hong;LIANG Jian-di;CHEN Hui-nan(Department of Reproductive Medicine,Dongguan People's Hospital,Dongguan 523000)
出处 《中国优生与遗传杂志》 2020年第12期1532-1534,1541,共4页 Chinese Journal of Birth Health & Heredity
关键词 三维能量多普勒超声 体外受精-胚胎移植 子宫内膜容受性 妊娠结局 Transvaginal 3D ultrasound In vitro fertilization-embryo transfer Endometrial receptivity Pregnancy outcome
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