摘要
由于来自外界压力的逐渐增加,睡眠障碍已经成为现代人的常见病。中药作为传统的治疗失眠手段,其临床效果已得到广大患者认可,而酸枣仁作为中医临床中常用的镇静催眠药因其在方剂中的配伍作用而获得睡眠方面研究者的关注。本文通过总结酸枣仁及其配伍组方改善睡眠的药理作用和相关机制,发现酸枣仁中皂苷类、黄酮类以及生物碱类成分可以影响大脑中睡眠相关神经递质,发挥改善睡眠的作用。
In recent years,sleep disorders have become a common disease of people in modern society due to the increasing pressure.TCM,as a traditional means of treatment for insomnia,its clinical effect has been recognized by the majority of patients,and Ziziphi Spinosae Semen has been paid more attention to by sleep researchers because of its effect of sedation and hypnosis in the prescription.This study summarized the pharmacological effects and mechanisms of Ziziphi Spinosae Semen and its compatibility in improving sleep,and it found that the effects of saponins,flavonoids and alkaloids in Ziziphi Spinosae Semen on sleep related neurotransmitters in brain,which could play a role in improving sleep.
作者
刘莹
管彤
梁昊都
李国玉
LIU Ying;GUAN Tong;LIANG Haodu;LI Guoyu(Harbin University of Commerce,Harbin 150076,China)
出处
《中医药信息》
2021年第3期82-86,共5页
Information on Traditional Chinese Medicine
基金
黑龙江省自然科学基金资助项目(H201304)
黑龙江省中医药管理局中医药中青年科技攻关项目(ZQG-48,ZHY2020-176)。
关键词
睡眠障碍
酸枣仁
改善睡眠
睡眠机制
Sleep disorders
Ziziphi Spinosae Semen
Sleep improvement
Sleep mechanism
