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维持性血液透析患者认知功能障碍与衰弱的相关性 被引量:16

Relationship between cognitive impairment and frailty in maintenance hemodialysis patients
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摘要 目的了解维持性血液透析患者认知功能及衰弱现状,并探讨认知功能障碍与衰弱的关系。方法采用便利抽样法选取连云港市3所医院的467例维持性血液透析患者为研究对象,采用一般资料问卷、简易精神状态检查量表及Fried衰弱表型评估方法进行横断面研究。结果维持性血液透析患者认知功能障碍发生率为28.7%,衰弱发生率为35.5%;Logistic回归分析结果显示,衰弱表型中的握力低和步速减慢是患者认知功能障碍的主要影响因素(P<0.05,P<0.01)。结论维持性血液透析患者认知功能易受损,衰弱发生率较高,衰弱是认知功能障碍的危险因素,对于握力及行走速度下降的患者,应重视其认知功能的评估,及早识别予以预见性干预。 Objective To investigate the current status of cognitive function and frailty in maintenance hemodialysis patients,and to explore the relationship between cognitive impairment and frailty.Methods A cross-sectional survey was conducted on 467 maintenance hemodialysis patients from 3 hospitals in Lianyungang City by convenience sampling.The survey instruments included general data questionnaire,the Mini-Mental State Examination,and the Fried frailty phenotype assessment components.Results The prevalence of cognitive impairment and frailty was 28.7%,35.5%respectively in maintenance hemodialysis patients.Logistic regression analysis showed that low grip strength and slowed gait in frailty phenotype were the main influencing factors of cognitive impairment(P<0.05,P<0.01).Conclusion Maintenance hemodialysis patients are prone to have impaired cognitive function and high prevalence of frailty.Frailty is a risk factor for cognitive impairment.For patients with decreased grip strength and gait speed,attention should be paid to the assessment of their cognitive function,so as to achieve early identification for targeted intervention.
作者 陈管洁 张海林 尹丽霞 杜晓菊 周起帆 张慧嫔 Chen Guanjie;Zhang Hailin;Yin Lixia;Du Xiaoju;Zhou Qifan;Zhang Huipin(Blood Purification Center,The Affiliated Lianyungang Hospital of Xuzhou Medical University,Lianyungang 222002,China)
出处 《护理学杂志》 CSCD 北大核心 2021年第6期27-31,共5页 Journal of Nursing Science
基金 连云港市卫生计生科技项目(201708)。
关键词 维持性血液透析 衰弱 认知功能障碍 握力 步速 maintenance hemodialysis frailty cognitive impairment grip strength gait speed
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