摘要
MR扩散峰度成像(DKI)基于多项式模型,能够量化组织中水分子的扩散运动与自由高斯运动的偏差。DKI技术可以定量评价组织微环境的复杂性和异质性,近年来已用于评价肾脏功能及相关疾病,在肾脏肿瘤的分级,以及在梗阻性肾病、糖尿病肾病、高尿酸血症肾病等常见疾病的早期诊断中具有一定的应用价值。就DKI成像原理及在正常肾脏和肾脏常见疾病中的研究进展予以综述。
Based on polynomial model,diffusion kurtosis imaging(DKI)could quantify the deviation between true diffusion motion and free Gaussian distribution motion of water molecules in biological tissues.DKI technology,which can quantify the complexity and heterogeneity of tissue microenvironment,has been gradually applied in the evaluation of renal function and related diseases in recent years,and shows promising clinical application prospect in renal tumor grading and the early diagnosis of obstructive nephropathy,diabetic nephropathy,hyperuricemia nephropathy,etc.This article aims to review the technical principles of DKI and its research advance in normal kidneys and general renal diseases.
作者
袁仪忠
崔建民
沈文(审校)
YUAN Yizhong;CUI Jianmin;SHEN Wen(First Central Hospital Institute,Tianjin Medical University,Tianjin 300192,China;Department of Radiology,Tianjin First Central Hospital)
出处
《国际医学放射学杂志》
北大核心
2021年第2期197-201,共5页
International Journal of Medical Radiology
基金
国家自然科学基金(81873888)。
关键词
磁共振成像
扩散峰度成像
肾脏
肾肿瘤
Magnetic resonance imaging
Diffusion kurtosis imaging
Kidney
Renal tumor
