摘要
荧光碳点由于其优异的光学和化学性能,近年来引起了人们的广泛关注。本研究以天然生物质胡萝卜为原料,通过水热法一步合成了粒径均匀的荧光生物质碳点(BCDs)。制备过程简单环保,所合成的荧光BCDs具有良好的耐光漂白能力和生物相容性,并成功应用于人膀胱癌活细胞荧光成像中。
Fluorescent carbon dots have attracted much attention in recent years due to their excellent optical and chemical properties.Fluorescence biomass carbon dots(BCDs)with uniform particle size were synthesized by hydrothermal method using natural biomass carrot as raw material.The preparation process is simple and environmentally friendly.The synthesized fluorescent BCDs exhibited excellent photo bleaching resistance and biocompatibility,and were applied successfully in live cell fluorescence imaging of human bladder cancer.
作者
杨克琴
Yang Keqin(Department of Chemistry and Pharmacy,Guilin Normal College,Guilin,Guangxi 541199,China)
基金
2018年广西自然科学基金项目“氨萘非特-喹啉酮衍生物-镧系金属配合物及其抗肿瘤作用机制研究”(2018GXNSFBA281188)
2018年桂林师范高等专科学校校级科研项目“生物质碳点-核酸适配体复合物在肿瘤靶向成像中的应用”(KYB201807)
2019年桂林师范高等专科学校桂北特色药资源研究中心科研项目“基于生物质碳点纳米探针的比率荧光成像以及肿瘤细胞中药物释放跟踪研究”(KYA201901)。
