摘要
骨质疏松性椎体压缩骨折(osteoprosis vertebral compression fracture,OVCF)是老年性及绝经后骨质疏松症患者最常见的严重并发症,骨折患者常有骨性疼痛、椎体高度下降、脊柱后凸畸形等临床表现,严重影响患者生活质量。经皮椎体成形术(percutaneous vertebroplasty,PVP)、经皮椎体后凸成形术(percutaneous kyphoplasty,PKP)及网袋加压椎体成形术(vesselplasty)是治疗OVCF的常用术式,在恢复椎体高度、预防后凸畸形、减轻疼痛症状等方面优势突出。但OVCF患者椎体成形术后存在非手术椎体再发骨折的可能性,在影响手术质量的同时,对患者术后康复、生活质量、经济负担均有较大影响。椎体成形术后非手术椎体再发骨折与骨质疏松进程、初始骨折部位及数量等自身客观因素相关,也与术后椎体高度的过度恢复、骨水泥渗漏、骨水泥过度填充等手术因素密切相关。本文通过查阅近年来关于OVCF患者椎体成形术后非手术椎体再发骨折危险因素及原因文献报道,综述经过统计学方法验证的,具有统计学意义的危险因素,通过患者自身因素、手术因素等方面展开探讨,以期能够为临床降低OVCF患者椎体成形术后再发骨折的发生率提供相关参考。
Osteoporosis vertebral compression fracture(OVCF) is the most common serious complication of senile and postmenopausal osteoporosis patients.Fracture patients often have bone pain,vertebral body height reduction,and kyphosis Malformation and other clinical manifestations seriously affect the patient’s quality of life.Percutaneous vertebroplasty(PVP),percutanous kyphoplasty(PKP) and mesh plasty(vesselplasty) are commonly used procedures for the treatment of OVCF.It has outstanding advantages in terms of body height,prevention of kyphosis,and relief of pain symptoms.However,there is the possibility of non-surgical vertebral fractures after vertebral plasty in OVCF patients,which not only affects the quality of surgery,but also has a great impact on patients’ postoperative rehabilitation,quality of life,and economic burden.The recurrent fracture of the adjacent vertebrae after vertebroplasty is related to its own objective factors such as the process of osteoporosis,the initial fracture site and the number of fractures,as well as the surgical factors such as excessive recovery of postoperative vertebral body height,bone cement leakage,and excessive bone cement filling.In this paper,through reviewing recent literature reports on the risk factors and causes of non-surgical vertebral fractures after vertebral plasty in OVCF patients,we review the statistically validated risk factors that have statistical significance.Discussions are conducted in order to provide relevant references for clinically reducing the incidence of recurrent fractures after vertebroplasty in OVCF patients.
作者
邓强
乔小万
李中锋
彭冉东
王雨榕
杜凯然
张凯东
罗林钊
DENG Qiang;QIAO Xiaowan;LI Zhongfeng;PENG Randong;WANG Yurong;DU Kairan;ZHANG Kaidong;LUO Linzhao(Gansu Provincial Hospital of Traditional Chinese Medicine,Lanzhou 730050,China;Gansu University of Traditional Chinese Medicine,Lanzhou 730000,China)
出处
《中国骨质疏松杂志》
CAS
CSCD
北大核心
2021年第4期613-617,624,共6页
Chinese Journal of Osteoporosis
基金
国家自然科学基金(地区)基金项目(81860860)
兰州市科技局社会发展项目(2017-RC-44)
白求恩·脊柱病理性骨折椎体强化治疗专项基金项目(BK-JP2018004)。
关键词
骨质疏松性椎体压缩骨折
椎体成形术
再骨折
因素
综述
osteoporotic vertebral compression fractures
vertebroplasty
re-fracture
factors
summary
