摘要
目的研究间苯三酚联合缩宫素对产程、宫颈损伤、中转剖宫产和母婴结局的影响。方法采用前瞻性随机临床对照研究设计,选取2019年5月1日至2020年5月1日阳春市妇幼保健院具有催产指征的孕妇100例为研究对象,随机分为两组,每组各50例。对照组仅给予催产药物缩宫素静脉滴注,而试验组给予间苯三酚联合缩宫素静脉滴注。观察两组产妇第一、二和三产程时间,产妇宫颈损伤情况(宫颈水肿、宫颈裂伤、宫颈感染),新生儿并发症发生率及Apgar评分的影响;同时观察两组产妇中转剖宫产率。结果试验组产妇的第一、二、三产程均明显短于对照组(t=4.362、2.154、1.093,P<0.05);试验组产妇的宫颈损伤总发生率低于对照组(χ^(2)=4.792,P<0.05);两组新生儿Apgar评分和并发症总发生率比较,差异无统计学意义(P>0.05);两组产妇中大部分顺利进行阴道分娩,仅少数产妇中转剖宫产,两组比较差异无统计学意义(P>0.05)。结论间苯三酚联合缩宫素疗法能够明显缩短产妇产程,降低产妇宫颈损伤发生率,且对新生儿并发症发生率及基本情况无明显影响,临床效果良好,值得进行推广。
Objective To research the impacts of phloroglucinol combined with oxytocin on labor process,cervical injury,transfer to cesarean section and maternal and infant outcomes.Methods A prospective randomized controlled clinical research design was adopted.A total of 100 pregnant women with indications for induced Labor admitted to Yangchun Maternal and Child Health Care Hospital from May 1,2019 to May 1,2020 were selected,and they were randomly divided into the control group(n=50)and the observation group(n=50).The control group was only treated with intravenous drip of oxytocin,while the observation group was treated with intravenous drip of phloroglucinol combined with oxytocin.The time of the first,second and third stages of labor,the maternal cervical injury(cervical edema,cervical laceration,cervical infection),the incidence of complications in infants and impact of Apgar score,as well as the conversion rate of cesarean section between the two groups were observed simultaneously.Results The first,second and third stages of labor in the experimental group were all significantly shorter than those in the control group(t=4.362,2.154,1.093,P<0.05).The total incidence of cervical injury in the experimental group of puerperae was lower than that in the control group(χ^(2)=4.792,P<0.05).There were no statistically significant differences in neonatal Apgar score and the total incidence of complications between the two groups(P>0.05).Most of the puerperae in the two groups performed vaginal delivery successfully,while only a few of them were transferred to cesarean section.There was no statistically statistical difference between the two groups(P>0.05).Conclusion The phloroglucinol combined with oxytocin therapy can obviously shorten the labor process and reduce the incidence of cervical injury,and it has no obvious impact on the incidence of neonatal complications and basic situation.Therefore,it has a good clinical efficacy and is worthy of promotion.
作者
伍冠
姜军
WU Guan;JIANG Jun(Yangchun Maternal and Child Health Care Hospital,Guangdong,Yangchun 529600,China)
出处
《中国医药科学》
2021年第6期65-67,共3页
China Medicine And Pharmacy
基金
广东省阳江市医疗卫生类科技计划项目(SF2020196)。
关键词
间苯三酚
缩宫素
产程
宫颈损伤
中转剖宫产
母婴结局
Phloroglucinol
Oxytocin
Labor process
Cervical injury
Transfer to cesarean section
Maternal and infant outcomes
