摘要
目的探讨子宫动脉超声血流指数与子宫颈癌患者预后的相关性。方法选取2018年8月至2021年1月间西安市人民医院收治的60例宫颈癌患者为观察组,同期选取60例因良性病变行子宫切除术的患者为对照组,均采用彩色多普勒超声检查,记录子宫动脉超声血流指数,判定宫颈癌浸润侵袭情况并进行相关性分析。结果观察组患者子宫动脉收缩期峰值流速(PSV)和舒张末期血流速度(EDV)值均高于对照组,阻力指数(RI)值低于对照组,差异均有统计学意义(均P <0.05)。观察组患者以Ⅲ级血流为主,对照组以Ⅱ级血流为主,两组半定量血流参数比较,差异有统计学意义(P <0.05)。观察组患者子宫动脉血管指数(Ⅵ)、血流指数(FI)和血管-血流指数(VFI)值均高于对照组,差异均有统计学意义(均P <0.05)。Logistic多因素回归分析显示,观察组患者子宫动脉PSV、EDV、Ⅵ、FI、VFI和Ⅲ级血流为宫颈癌浸润侵袭的主要影响因素(均P <0.05)。结论子宫动脉超声血流指数与宫颈癌患者浸润侵袭存在相关性,能反映宫颈癌新生血管情况,为宫颈癌的诊断提供更多信息。
Objective To investigate the correlation between the uterine artery ultrasound blood flow indexes and prognosis of cervical cancer.Methods Sixty patients with cervical cancer who visited Xi'an People's Hospital/Xi'an Fourth Hospital were selected and included in an observation group,and 60 patients who underwent hysterectomy for benign lesions at the same hospital were selected and included in a control group from August 2018 to January 2021.Color Doppler ultrasonography was used and the uterine artery ultrasound blood flow indexes were recorded.The infiltration and invasion status in cervical cancer was determined and the association between the uterine artery ultrasound blood flow indexes and prognosis of cervical cancer was analyzed.Results The uterine artery peak systolic velocity(PSV)and end-diastolic blood flow velocity(EDV)were higher in the observation group than in the control group and resistance index(RI)was lower in the observation group than in the control group(all P<0.05).GradeⅢblood flow held overwhelming majority in the observation group,and gradeⅡblood flow held overwhelming majority in the control group(all P<0.05).There were significant differences in semi-quantitative blood flow parameters(all P<0.05).The uterine artery blood flow index(FI),vascular index(VI)and blood vessel-blood flow index(VFI)were higher in the observation group than in the control group(all P<0.05).Logistic multivariate regression analysis showed that uterine artery PSV,EDV,VI,FI,VFI,and gradeⅢblood flow were the main factors influencing invasion and invasion in cervical cancer in the observation group(all P<0.05).Conclusion Uterine artery ultrasound blood flow indexes are associated with infiltration and invasion in cervical cancer,which can reflect the neovascularization of cervical cancer and provide more information for the diagnosis of cervical cancer.
作者
石洋
马文娟
SHI Yang;MA Wen-juan(Department of Function,Traditional Chinese Medicine Hospital of Yanta District,Xi'an 710000,China;Department of Gynecology,Xi'an People's Hospital/Xi'an Fourth Hospital,Xi'an 710032,China)
出处
《中国肿瘤临床与康复》
2021年第4期404-407,共4页
Chinese Journal of Clinical Oncology and Rehabilitation
关键词
子宫动脉
超声血流指数
宫颈肿瘤
浸润侵袭
预后
相关性
Uterine artery
Ultrasound blood flow indices
Cervical neoplasms
Infiltration and invasion
Prognosis
Association
