摘要
目的探讨经直肠与经会阴前列腺癌穿刺活检的检出率及安全性。方法回顾性分析2015年5月—2020年1月江苏省人民医院溧阳分院泌尿外科收治的行经直肠前列腺穿刺活检术的80例患者(经直肠组)及行经会阴前列腺穿刺活检术的80例患者(经会阴组)。比较两组一般资料、前列腺癌检出率、并发症发生情况、前列腺癌患者根治术围术期情况。结果两组年龄、体重指数、结节最长经、结节数目、前列腺体积、总前列腺特异性抗原、Gleason评分、穿刺针数、阳性穿刺针数、不合格样本针数比较,差异无统计学意义(P>0.05)。经会阴组穿刺时间长于经直肠组(P<0.01)。两组前列腺癌检出率比较,差异无统计学意义(P>0.05)。经会阴组并发症总发生率低于经直肠组(P<0.01)。经会阴组穿刺至根治术的间隔、根治术手术时间短于经直肠组,术中出血量、术中前列腺组织粘连率低于经直肠组(P<0.05或P<0.01)。两组手术切缘阳性率比较,差异无统计学意义(P>0.05)。结论与经直肠前列腺癌穿刺活检比较,经会阴穿刺活检具有更高安全性,对根治术负面影响小。
Objective To investigate the detection rate and safety of transrectal and transperineal puncture biopsy for prostate cancer.Methods Retrospective analysis was performed on 80 patients undergoing transrectal prostate puncture biopsy(transrectal group)and 80 patients undergoing transperineal prostate puncture biopsy(transperineal group)admitted to the Department of Urology,Liyang Branch of Jiangsu Provincial People’s Hospital from May 2015 to January 2020 were selected.The general data,the detection rate of prostate cancer,the occurrence of complications,and the perioperative conditions of prostate cancer patients undergoing radical resection were compared between two groups.Results There were no significant differences in age,body mass index,longest nodules meridian,number of nodules,prostate volume,total prostate specific antigen,Gleason score,number of puncture needles,number of positive puncture needles and number of unqualified samples between two groups(P>0.05).The puncture time in transperineal group was longer than that in transrectal group(P<0.01).There was no significant difference in the detection rate of prostate cancer between two groups(P>0.05).The incidence of total complications in transperineal group was lower than that in transrectal group(P<0.01).The interval of puncture to radical operation,radical operation time in transperineal group were shorter than those in transrectal group,and intraoperative blood loss,intraoperative prostate tissue adhesion rate were lower than those in transrectal group(P<0.05 or P<0.01).Conclusion Compared with transrectal prostate cancer puncture biopsy,transperineal puncture biopsy has higher safety and less negative impact on radical surgery.
作者
蒋科
杭震宇
马鸿翔
吴鸣
JIANG Ke;HANG Zhenyu;MA Hongxiang;WU Ming(Department of Urology,Liyang Branch of Jiangsu Provincial People’s Hospital,Jiangsu Province,Changzhou 213300,China)
出处
《中国医药导报》
CAS
2021年第14期103-106,共4页
China Medical Herald
基金
江苏省研究生实践创新计划项目(SJCX18_0067)。
关键词
经直肠
经会阴
前列腺癌
穿刺
活检
安全性
Transrectal
Transperineal
Prostate cancer
Puncture
Biopsy
Safety
