摘要
目的:探究妇产科Ⅱ类切口手术患者围术期预防性应用抗菌药物合理性。方法:回顾性分析本院2019年1月—2021年1月妇产科住院患者300份病历,提取资料中的有关预防性应用抗菌药物的信息,用本院自制调查表统计本院妇产科Ⅱ类切口手术患者围术期预防性应用抗菌药物的使用次数、预防用药时间、联合用药情况等,并对不合理用药类型进行分析讨论。结果:所有患者均使用了预防性抗菌药物(100%),共使用568次,使用次数最多是头孢菌素类(32.9%),第二是硝基咪唑类(24.5%)。研究显示有160例患者为单一用药,占比53.3%,平均预防用药时间为(5.5±1.8)d;有140例患者为二联用药,占比为46.7%,平均预防用药时间为(4.1±1.1)d;没有发现三联或者三联以上的用药情况。其中,不合理使用有269例,占比89.7%,主要包括持续给药时间过长(36.4%)、给药时间不合理(26.0%)、药品溶媒选择不当(24.5%)、联合用药不合理(7.1%)、用药次数过多(5.9%)。结论:本院围术期预防性应用抗菌药物问题较多,需进一步规范,采用干预手段,提高用药合理性。
Objective: To explore the rationality of perioperative prophylactic use of antibiotics in patients with type Ⅱ incision surgery in obstetrics and gynecology. Methods: 300 cases of inpatients in obstetrics and gynecology from January 2019 to January 2021 were retrospectively analyzed to extract the information about prophylactic use of antibiotics, Used our self-made questionnaire to count the number of perioperative use of prophylactic antibiotics, the time of preventive medication, and the combined use of antimicrobial drugs in patients with class Ⅱ incision surgery in the Department of Obstetrics and Gynecology in our hospital, and the types of unreasonable medications for analysis and discussion. Results: all patients used prophylactic antibiotics(100%), a total of 568 times, the first is cephalosporins used most(32.9%), the second is nitroimidazoles(24.5%). 127 patients were treated with single drug, accounting for 42.3%, and the average preventive medication time was(5.5±1.8) d;173 patients were treated with double drug, accounting for 57.7%, and the average preventive medication time was(4.1±1.1) d;and no triple or more drug use was found. There were 269 cases of irrational drug use, accounting for 89. 7%, included long duration of Administration(36.4%), unreasonable administration time(26.0%), improper choice of drug solvent(24.5%), unreasonable combination of drugs(7.1%) and excessive use of drugs(5. 9%). Conclusion: there are many problems in perioperative prophylactic use of antibiotics in our hospital, which need to be further standardized, and intervention measures should be adopted to improve the rationality of drug use.
作者
孙丹丹
刁斌
SUN Dandan;DIAO Bin(Zhongyi Northeast International Hospital Co.,Ltdgynaecology,Liaoning Shenyang 110000)
出处
《中国药物滥用防治杂志》
CAS
2021年第3期314-317,326,共5页
Chinese Journal of Drug Abuse Prevention and Treatment
关键词
妇产科
围术期
预防性抗菌药物
合理用药
Obstetrics and Gynecology
Perioperative
Preventive antibiotics
Rational drug use
