摘要
抑郁症作为一种心境障碍,在全球范围内影响超过3亿人,已经成为全球残疾的主要原因,病情严重时甚至可导致自杀。重复经颅磁刺激(repetitive transcranial magnetic stimulation,rTMS)作为一种无创的非侵入性的抗抑郁治疗手段,利用脉冲磁场作用于中枢神经系统,影响脑内代谢和神经电活动,从而改善抑郁症患者的症状。作者从rTMS的治疗靶点和模式以及通过磁共振成像对rTMS效果的评估进行综述,以提高对rTMS改善抑郁症的核心症状的认识。
Depression,as a mood disorder,has become the main course of global disability.It has affected more than 300 million people worldwide and can even lead to suicide in severe cases.Repetitive transcranial magnetic stimulation(rTMS),as a non-invasive antidepressant therapy,can improve the symptoms of patients with depression by using pulsed magnetic fields,which can act on the central nervous system to affect brain metabolism and neuroelectrical activity.This article summarizes from these following aspects——the therapeutic targets and modes of rTMS and the effect evaluation of rTMS through magnetic resonance imaging,in order to improve the understanding of rTMS in ameliorating the core symptoms of depression.
作者
杨克硕
刘肖肖
白岩
王梅云
陈传亮
YANG Keshuo;LIU Xiaoxiao;BAI Yan;WANG Meiyun;CHEN Chuanliang(Department of Medical Imaging,Zhengzhou University People's Hospital,Henan Province People's Hospital,Zhengzhou 450003,China;Department of Medical Imaging,People's Hospital of Henan University,Henan Provincial People's Hospital,Zhengzhou 450003,China)
出处
《磁共振成像》
CAS
CSCD
北大核心
2021年第7期90-93,共4页
Chinese Journal of Magnetic Resonance Imaging
基金
国家重点研发计划项目(编号:2017YFE0103600)
国家自然科学基金项目(编号:81720108021)。
关键词
抑郁症
重复经颅磁刺激
核心症状
磁共振成像
depression
repetitive transcranial magnetic stimulation
core symptom
magnetic resonance imaging
