摘要
目的探讨胃得安胶囊联合兰索拉唑治疗胃溃疡的临床效果。方法66例胃溃疡患者,根据治疗方式的不同分为常规组和研究组,每组33例。常规组患者应用兰索拉唑胶囊治疗,研究组患者选择兰索拉唑联合胃得安胶囊治疗。比较两组患者治疗效果、不良反应发生情况以及治疗前后的典型症状评分。结果研究组治疗总有效率96.97%高于常规组的78.79%,差异具有统计学意义(P<0.05)。研究组不良反应发生率6.06%低于常规组的27.27%,差异具有统计学意义(P<0.05)。治疗后,研究组患者中上腹痛评分(0.45±0.01)分、反酸程度评分(0.41±0.01)分均低于常规组的(1.03±0.15)、(1.42±0.21)分,差异均具有统计学意义(P<0.05)。结论对胃溃疡患者应用胃得安胶囊联合兰索拉唑治疗后效果显著,能够有效降低不良反应发生率,提升治疗效果,改善临床症状,值得推广。
Objective To discuss the clinical effect of Weidean capsule combined with lansoprazole in the treatment of gastric ulcer.Methods A total of 66 patients with gastric ulcer were divided into conventional group and research group according to different treatment methods,with 33 cases in each group.The conventional group was treated with lansoprazole capsule,and the research group was treated with lansoprazole and Weidean capsule.The therapeutic effect,occurrence of adverse reactions,and typical symptom scores before and after treatment were compared between the two groups.Results The total effective rate 96.97%of the research group was higher than 78.79%of the conventional group,and the difference was statistically significant(P<0.05).The incidence of adverse reactions 6.06%of the research group was lower than 27.27%of the conventional group,and the difference was statistically significant(P<0.05).After treatment,the upper and middle abdominal pain score(0.45±0.01)points and acid reflux score(0.41±0.01)points of the research group were lower than(1.03±0.15)and(1.42±0.21)points of the conventional group,and the difference was statistically significant(P<0.05).Conclusion Combination of Weidean capsule and lansoprazole has remarkable effect on patients with gastric ulcer,and it can effectively lower the incidence of adverse reactions,improve therapeutic effect,and improve clinical symptoms,which is worthy of promotion.
作者
许淑敏
XU Shu-min(Changtu County Central Hospital,Tieling 112599,China)
出处
《中国现代药物应用》
2021年第13期138-140,共3页
Chinese Journal of Modern Drug Application
关键词
胃溃疡
胃得安胶囊
兰索拉唑
临床效果
Gastric ulcer
Weidean capsule
Lansoprazole
Clinical effect
