摘要
目的:探究并分析2017-2019年医院感染患者病原菌分布及耐药性。方法:选取2017年1-12月120例医院感染患者为A组,2018年1-12月109例医院感染患者为B组,2019年1-12月93例医院感染患者为C组。比较三组的病原菌分布情况及主要病原菌的耐药性情况。结果:A组共检出126株病原菌,B组共检出116株病原菌,C组共检出101株病原菌。A组革兰阴性菌检出率为55.56%(70/126),革兰阳性菌检出率为40.48%(51/126),真菌检出率为3.97%(5/126)。B组革兰阴性菌检出率为56.90%(66/116),革兰阳性菌检出率为40.52%(47/116),真菌检出率为2.59%(3/116)。C组革兰阴性菌检出率为74.26%(75/101),革兰阳性菌检出率为23.76%(24/101),真菌检出率为1.98%(2/101)。三组的革兰阴性菌检出率均高于革兰阳性菌及真菌的检出率。C组的革兰阴性菌检出率高于A、B组,差异均有统计学意义(χ^(2)=8.498、7.151,P<0.05)。A、C组铜绿假单胞菌和大肠埃希菌及B组大肠埃希菌对氨苄西林、头孢唑林及环丙沙星的耐药率均高于其他药物。B组铜绿假单胞菌氨苄西林、头孢唑林及环丙沙星的耐药率均高于头孢曲松、头孢噻肟、亚胺培南、庆大霉素及哌拉西林。三组主要革兰阳性菌对青霉素及红霉素的耐药率均高于其他药物。结论:2017-2019年医院感染患者的病原菌仍以革兰阴性菌为主,主要革兰阴性菌及革兰阳性菌对各类药物的耐药率并未见显著变化。
Objective:To investigate and analyze the pathogens distribution and drug resistance of patients with nosocomial infection from 2017 to 2019.Method:A total of 120 patients with nosocomial infection from January to December 2017 were selected as group A,109 patients with nosocomial infection from January to December 2018 were selected as group B,and 93 patients with nosocomial infection from January to December 2019 were selected as group C.The distribution of pathogenic bacteria and drug resistance of main pathogenic bacteria were compared among the three groups.Result:A total of 126 strains of pathogenic bacteria were detected in group A,116 strains in group B and 101 strains in group C.The positive rate of Gram-negative bacteria was 55.56%(70/126),Gram-positive bacteria was 40.48%(51/126),and fungus was 3.97%(5/126)in group A.The positive rate of Gram-negative bacteria was 56.90%(66/116),Gram-positive bacteria was 40.52%(47/116),and fungus was 2.59%(3/116)in group B.The positive rates of Gram-negative bacteria,Gram-positive bacteria and fungus in group C were 74.26%(75/101),23.76%(24/101)and 1.98%(2/101).The detection rate of Gram-negative bacteria were higher than those of Gram-positive bacteria and fungus of three groups.The positive rate of Gram-negative bacteria of group C was higher than those of group A and B,and the differences were statistically significant(χ^(2)=8.498,7.151,P<0.05).The drug resistance rates of pseudomonas aeruginosa and escherichia coli of group A and C and escherichia coli of group B to Ampicillin,Cefazolin and Ciprofloxacin were higher than those of other drugs.The drug resistance rates of pseudomonas aeruginosa of group B to Ampicillin,Cefazolin and Ciprofloxacin were higher than those of Ceftriaxone,Cefotaxime,Imipenem,Gentamicin and Piperacillin.The drug resistance rates of the main Grampositive bacteria to Penicillin and Erythromycin of three groups were higher than those of other drugs.Conclusion:The pathogens of patients with nosocomial infection from 2017 to 2019 are main Gram-negative bacteria,the change of drug resistance of main Gram-negative bacteria and Gram-positive bacteria to all kinds of drugs are not significant.
作者
麦艺敏
邓媛
MAI Yimin;DENG Yuan(Xingtan Hospital Affiliated Shunde Hospital of Southern Medical University,Foshan 528325,China;不详)
出处
《中国医学创新》
CAS
2021年第17期80-83,共4页
Medical Innovation of China
关键词
医院感染
病原菌分布
耐药性
Nosocomial infection
Pathogens distribution
Drug resistance
