摘要
目的:探讨磁共振图像在宫颈癌患者容积旋转放疗中的应用效果及对摆位误差和累积剂量血的影响。方法:选择2017年3月-2018年12月宫颈癌患者154例为对象,所有患者均采用容积旋转放疗治疗,随机数字表法分为两组,各77例。对照组治疗时采用CT图像进行定位干预,观察组采用磁共振图像定位干预,3个月治疗后评估患者效果,疗程完成后进行12个月随访,比较两组摆位误差、累积剂量学、毒副反应及死亡率。结果:观察组放疗期间摆位误差及治疗期间腹围下降幅度均低于对照组(P<0.05), 观察组直肠V30、V40及V50辐射剂量、膀胱V40及V50辐射剂量及股骨头平均剂量均少于对照组(P<0.05), 两组治疗后1、6个月死亡率差异无统计学意义(P>0.05), 观察组治疗后12个月死亡率、治疗期间急性膀胱反应、急性肠道腹泻及恶心呕吐发生率均低于对照组(P<0.05)。结论:磁共振图像用于宫颈癌患者容积旋转放疗中能降低摆位误差,可减少周围组织放疗剂量,毒副反应发生率较低,有助于降低患者死亡率,获得良好的预后,值得推广应用。
Objective:To investigate the application effect of magnetic resonance imaging in volume rotation radiotherapy for cervical cancer patients and its effect on the positioning error and accumulated dose blood.Method:A total of 154 patients with cervical cancer from March 2017 to December 2018 were selected as subjects.All patients were treated with volumetric rotation radiotherapy,and randomly divided into two groups with 77 patients in each group by number table method.CT images were used for localization intervention in the control group,and magnetic resonance images were used for localization intervention in the observation group.After 3 months of treatment,the efficacy of patients was evaluated.After 12 months of treatment,the positioning error,cumulative dosimetry,toxic side effects and mortality were compared between the two groups.Result:The positioning error and the abdominal circumference of cervical cancer patients in the observation group was lower than that in the control group(P<0.05).The radiation doses of V30,V40 and V50 in rectum,V40 and V50 in bladder and average dose of femoral head in the observation group were lower than those in the control group(P<0.05).The mortality rate at 1 and 6 months after treatment was not statistically significant in the two groups(P>0.05).The mortality rate at 12 months after treatment,the incidence of acute bladder reaction,acute intestinal diarrhea,nausea and vomiting in observation group were lower than those in control group(P<0.05).Conclusion:Magnetic resonance images used in volume rotation radiotherapy for cervical cancer patients can reduce the positioning error,can reduce the radiation dose of surrounding tissues,the incidence of toxic reactions is low,help to reduce the mortality of patients,obtain a good prognosis,worthy of promotion and application.
作者
李斯
李典育
余枭
LI Si;LI Dianyu;YU Xiao(Southern Hospital,Southern Medical University,Guangzhou 510515,China;不详)
出处
《中外医学研究》
2021年第20期90-93,共4页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
磁共振图像
宫颈癌
容积旋转放疗
摆位误差
累积剂量学
毒副反应
死亡率
Magnetic resonance imaging
Cervical cancer patients
Volumetric rotary radiotherapy
Pendulum error
Cumulative dosimetry
Toxic and side effects
Mortality rate
