摘要
目的探讨基于行动研究法理论的健康管理在老年非酒精性脂肪性肝病(NAFLD)患者中的应用效果。方法收集2018年1月至2020年1月于新疆医科大学附属中医医院肝病科就诊的110例老年NAFLD患者,按照随机数字表法分为对照组和观察组,每组各55例。对照组给予常规模式健康管理干预,观察组给予基于行动研究法理论的健康管理干预,干预时间均为6个月。采用自我感受负担量表(SPBS)评价患者自我感受负担。比较两组干预前后肝功能指标、肝纤维化指标、疾病认知得分、健康行为变化及SPBS评分。结果干预后,两组丙氨酸氨基转移酶、天门冬氨酸氨基转移酶、总胆红素水平低于干预前,且观察组低于对照组,差异有统计学意义(P <0.05)。干预后,两组黏连蛋白、透明质酸、Ⅲ型前胶原、Ⅳ型胶原水平低于干预前,且观察组低于对照组,差异有统计学意义(P <0.05)。干预后,两组疾病特征知识、饮食知识、运动知识和用药知识得分高于干预前,且观察组高于对照组,差异有统计学意义(P <0.05)。结论基于行动研究法理论的健康管理能够改善老年NAFLD患者的肝功能,减轻肝纤维化程度,提高疾病认知水平,促进健康行为建立,并减轻疾病自我感受负担,临床上值得进一步推广。
Objective To explore the application effect of health management based on the theory of action research in elderly patients with non-alcoholic fatty liver disease(NAFLD).Methods A total of 110 elderly NAFLD patients who were treated in the Department of Hepatology,Traditional Chinese Medicine Hospital Affiliated to Xinjiang Medical University from January 2018 to January 2020 were collected.According to the random number table method,they were divided into control group and observation group,with 55 cases in each group.The control group was given a routine health management intervention,and the observation group was given a health management intervention based on the theory of action research method.The duration of the intervention was six months.The self-perceived burden scale(SPBS)was used to evaluate the self-perceived burden of patients.The liver function indexes,liver fibrosis indexes,disease cognition scores,health behavior changes and SPBS scores were compared between the two groups before and after intervention.Results After the intervention,the levels of alanine aminotransferase,aspartate aminotransferase,and total bilirubin in the two groups were lower than those before the intervention,while the observation group was lower than the control group,and the differences were statistically significant(P<0.05).After the intervention,the levels of adhesion protein,hyaluronic acid,typeⅢprocollagen,and typeⅣcollagen in the two groups were lower than those before the intervention,while the observation group was lower than the control group,and the differences were statistically significant(P<0.05).After the intervention,the scores of disease characteristic knowledge,dietary knowledge,exercise knowledge,and medication knowledge in the two groups of disease cognition were higher than those before the intervention,while the observation group was higher than the control group,and the differences were statistically significant(P<0.05).Conclusion Health management based on the theory of action research can improve the liver function of elderly NAFLD patients,reduce the degree of liver fibrosis,increase the level of disease awareness,promote the establishment of healthy behaviors,and reduce the burden of disease self-perception.It is clinically worthy of further promotion.
作者
杜惠玲
王燕
DU Huiling;WANG Yan(Department of Hepatology,Traditional Chinese Medicine Hospital Affiliated to Xinjiang Medical University,Xinjiang Uygur Autonomous Region,Urumqi 830000,China)
出处
《中国医药导报》
CAS
2021年第19期163-167,共5页
China Medical Herald
基金
国家自然科学基金资助项目(81860808)。
关键词
行动研究法
老年
非酒精性脂肪性肝病
疾病认知
健康管理
自我感受负担
Action research method
Elderly
Non-alcoholic fatty liver disease
Disease cognition
Health management
Self-perceived burden
