摘要
目的研究子宫肌瘤发病影响因素,指导相关防治工作。方法以2020年2月至2021年1月攀枝花市某医院首次确诊的子宫肌瘤病例为病例组,按年龄±0.05岁、BMI±0.05以1∶1比例选择同期在医院体检中心进行体检的非子宫肌瘤女性为对照组进行问卷调查,内容包括年龄、身高、体重、流产史、生育史、月经紊乱情况、妇科炎症患病情况、子宫内膜异位症、家族遗传史、焦虑、抑郁、体育锻炼、睡眠时间、长期(>6个月)口服避孕药等情况,采用单、多因素分析方法对子宫肌瘤和非子宫肌瘤健康体检者相关因素进行分析。结果子宫肌瘤患者551例、非子宫肌瘤女性563人调查资料齐全。病例组年龄以46~59岁为主,占45.37%,BMI以18.5~23.9为主,占57.35%;有流产史者占23.41%,有生育史者占73.50%。对照组46~59岁者占41.56%,BMI 18.5~23.9者占58.61%,有流产史者占16.52%,有生育史者占70.34%。病例组和对照组的年龄、BMI、生育史、子宫内膜异位症、体育锻炼、睡眠时间等分布差异均无统计学意义(均P>0.05)。多因素Logistic回归分析结果显示有流产史(OR=1.468)、有月经紊乱(OR=1.273)、有妇科炎症(OR=1.562)、有家族遗传史(OR=1.487)、焦虑(OR=1.996)、抑郁(OR=2.474)以及长期口服避孕药(OR=2.223)是子宫肌瘤发病的危险因素。结论子宫肌瘤发病受到流产史、月经紊乱、妇科炎症、家族遗传史、焦虑、抑郁、长期口服避孕药等多因素的影响,应指导女性保持良好心理状态、避免流产、重视生殖系统健康,以降低子宫肌瘤患病风险。
Objective To study the influencing factors of hysteromyoma and guide the related prevention and treatment.Methods Taking the cases of hysteromyoma diagnosed for the first time in a hospital in Panzhihua from February 2020 to January 2021 as the case group,according to age±0.05 years,BMI±0.05 and a ratio of 1:1 to select women without hysteromyoma who undergoing physical examination at the hospital physical examination center in the same period as the control group.Questionnaire survey was conducted,including age,height,weight,abortion history,childbearing history,menstrual irregularity,gynecological inflammation,endometriosis,family genetic history,anxiety,depression,physical exercise,sleep duration,long-term(>6 months)oral contraceptives,etc.Univariate and multivariate analysis methods were used to analyze the related factors of women with or without hysteromyoma.Results The survey data of 551 patients with hysteromyoma and 563 women without hysteromyoma were complete.In the case group,the age was mainly 46-59 years old,accounting for 45.37%;and the BMI was mainly 18.5-23.9,accounting for 57.35%;23.41%had abortion history and 73.50%had childbearing history.In the control group,41.56%were 46-59 years old,58.61%were BMI 18.5-23.9,16.52%had abortion history and 70.34%had childbearing history.There were no significant differences in age,BMI,childbearing history,endometriosis,physical exercise and sleep duration between the two groups(all P>0.05).Multivariate Logistic regression analysis showed that abortion history(OR=1.468),menstrual irregularity(OR=1.273),gynecological inflammation(OR=1.562),family history of disease(OR=1.487),anxiety(OR=1.996),depression(OR=2.474)and long-term oral contraceptives(OR=2.223)were risk factors for the onset of hysteromyoma.Conclusion Hysteromyoma is affected by many factors such as abortion history,menstrual irregularity,gynecological inflammation,family history of disease,anxiety,depression,long-term oral contraceptives.Women should be guided to maintain a good psychological state,avoid abortion,and attention to reproductive system health to reduce the incidence of hysteromyoma.
作者
陈娟
宋化雨
程瑶瑶
谢佳
CHEN Juan;SONG Hua-yu;CHENG Yao-yao;XIE Jia(Panzhihua Hospital of Integrated Traditional Chinese and Western Medicine,Panzhihua 617000,China)
出处
《华南预防医学》
2021年第7期844-847,共4页
South China Journal of Preventive Medicine
关键词
女性
子宫肌瘤
妇科
病例对照
影响因素
Women
Hysteromyoma
Gynecology
Case-control
Influencing factor
