摘要
目的:分析定量CT(QCT)与MRI非对称回波的最小二乘估算法迭代水脂分离序列(IDEAL-IQ)在2型糖尿病患者胰腺脂肪含量测定中的相关性及一致性。方法:纳入67例2型糖尿病志愿者,男性33例、女性34例,平均年龄(66.55±6.23)岁。用MRI IDEAL-IQ技术及QCT对患者的胰腺头、体及尾部区域的脂肪含量进行定量测量,获得患者的MRI胰腺脂肪分数(MR-PFF)及CT胰腺脂肪分数(CT-PFF)。对MR-PFF与CT-PFF进行相关性分析,并进行Bland-Altman一致性分析。同时分析MR-PFF与肝脏脂肪含量、腹围、体质量指数(BMI)等的相关性。结果:67例受试者平均腹围(83.34±10.1)cm、平均BMI(24.02±2.96)kg/m^(2),平均肝脏脂肪含量(5.28±2.76)%。腹围及肝脏脂肪含量与MR-PFF相关(P<0.05)。MR-PFF和CT-PFF分别为(12.21±10.71)%、(19.9±10.61)%,两者呈显著线性相关(r=0.842,P<0.001),MR-PFF=-4.169+0.818×CT-PFF;Bland-Altman分析示两者一致性较好(95%CI-4.15%~19.75%,P=0.044),3例样本在该区间外。结论:QCT与MRI测量的胰腺脂肪含量有明显的相关性和很好的一致性,可用于胰腺脂肪含量的定量测量。
Objective:To analyze the correlation and consistency of MRI IDEAL-IQ and quantitative CT(QCT)in the quantitation of pancreatic fat content in patients with type 2 diabetes.Methods:Sixty-seven volunteers with type 2 diabetes(33 men and 34 women,mean age[66.55±6.23]years)underwent both MRI IDEAL-IQ and QCT examinations.The regions of interest(ROI)were placed at the head,body,and tail of the pancreas to obtain MRI pancreas fat fraction(MR-PFF)and CT-PFF.The correlation between MR-PFF and CT-PFF was analyzed,and the consistency of them was analyzed by Bland-Altman.The correlations between MR-PFF and liver fat content,abdominal circumference,and body mass index(BMI)were also analyzed.Results:In sixty-seven volunteers,the mean abdominal circumference was(83.34±10.1)cm,BMI was(24.02±2.96)kg/m ^(2),and liver fat content was(5.28±2.76)%.The abdominal circumference and liver fat content were correlated with MR-PFF(P<0.05).MR-PFF and CT-PFF were(12.21±10.71)%and(19.9±10.61)%,respectively.CT-PFF showed a significant linear correlation with MR-PFF(r=0.842,P<0.001).MR-PFF=-4.169+0.818×CT-PFF.The Bland-Altman analysis results showed that the 95%CI of consistency was-4.15%-19.75%(P=0.044),and there were 3 values outside of the interval.Conclusions:The pancreatic fat contents measured by QCT and MRI have good correlation and consistency,and QCT can be used to measure pancreatic fat content.
作者
朱红
张宗军
吴飞云
ZHU Hong;ZHANG Zong-jun;WU Fei-yun(Department of Radiology,the First Affiliated Hospital of Nanjing Medical University,Nanjing 210029,Jiangsu,China;Department of Radiology,the Integrated Traditional Chinese and Western Medicine Affiliated Hospital of Nanjing University of Traditional Chinese Medicine,Nanjing 210028,Jiangsu,China)
出处
《中国临床医学》
2021年第4期598-602,共5页
Chinese Journal of Clinical Medicine
基金
江苏省自然科学基金面上项目(BK20201494).
关键词
脂肪胰
2型糖尿病
磁共振
定量CT
胰腺脂肪分数
fatty pancreas
type 2 diabetes
magnetic resonance
quantitative CT
pancreas fat fraction
