摘要
针对再生丝素蛋白水凝胶形貌不可控、凝胶速度慢、压缩性能差的问题,提出了一种乙酸-乙醇体系共同促进丝素蛋白快速凝胶的方法。通过研究相同酸性条件下,不同质量分数乙醇对水凝胶形貌、聚集态结构、热稳定性、压缩性能等的影响,探索水凝胶内部纤维结构的成形条件以及不同形貌下水凝胶的结构与性能差异。结果表明:相同酸性条件下随着乙醇质量分数的提高,水凝胶的结构与性能均得到改善,凝胶时间由12~14 h缩减到1 h左右,水凝胶形貌逐渐由几十到几百微米的孔洞结构向纤维结构转变,水凝胶中丝素蛋白结构以β-折叠为主;当乙醇质量分数为5.0%时,纤维直径为(1.09±0.5)μm,在干态下应变为60%时的压缩强度为(75.16±3.79)kPa,在湿态下压缩回复率达到伸长的63%。
In order to achieve the controllable morphology of silk fibroin hydrogel and to improve the gelling speed and compression properties,a simple fabrication method for silk fibroin hydrogel in acid-alcohol system was developed.This paper reports the effect of alcohol with different mass ratio on the morphology,aggregation structure,thermal property and compressive property of hydrogel at the same acidic condition.The research explored the forming conditions for silk fibroin hydrogels,and the differences in structure and properties of hydrogel.The results show that the structure and properties of hydrogels are improved with increased use of alcohol,which also benefited the gelation time reduction from 12-14 h to 1 h.In relation to this,the morphology of hydrogel gradually changes from pore to fibrous state.Moreover,the crystallization structure of silk fibroin in hydrogels was found to be mainlyβ-sheet.When the mass ratio of alcohol was set to 5.0%,the fiber diameter reached(1.09±0.5)μm.The hydrogels demonstrated a compressive strength of(75.16±3.79)kPa at 60%strain in dry state,and the compression recovery rate reached 63%in wet state.
作者
刘浩
路明磊
黄晓卫
王娜
王雪芳
宁新
明津法
LIU Hao;LU Minglei;HUANG Xiaowei;WANG Na;WANG Xuefang;NING Xin;MING Jinfa(College of Textiles & Clothing, Qingdao University, Qingdao, Shandong 266071, China;Industrial Research Institute of Nonwovens & Technical Textiles, Qingdao University, Qingdao, Shandong 266071, China;Shandong Special Nonwoven Materials Engineering Research Center, Qingdao, Shandong 266071, China)
出处
《纺织学报》
EI
CAS
CSCD
北大核心
2021年第8期41-48,共8页
Journal of Textile Research
基金
中国博士后科学基金项目(2016M592141)
山东省博士后科学基金项目(201603067)。
关键词
丝素蛋白
水凝胶
酸-醇体系
压缩性能
聚集态结构
医用材料
silk fibroin
hydrogel
acid-alcohol system
compression property
crystallization structure
medical material
