摘要
目的分析胸腔镜根治术对早期肺癌患者免疫功能的影响。方法选择2018年1月-2021年1月宣城市中心医院诊治的早期肺癌患者92例作为研究对象,根据手术方式不同分为胸腔镜组和对照组,每组46例。对照组实施传统开胸根治术,胸腔镜组实施胸腔镜根治术,比较两组围术期指标、免疫功能、肺功能、VAS评分及并发症发生情况。结果胸腔镜组手术时间、首次下床时间、住院时间短于对照组,术后引流量少于对照组,淋巴结清扫数量多于对照组,差异有统计学意义(P<0.05);胸腔镜组IgG水平低于对照组,CD3^(+)、CD4^(+)、NK水平高于对照组,差异有统计学意义(P<0.05);胸腔镜组FEV1、MV水平高于对照组,差异有统计学意义(P<0.05);胸腔镜组术后1、12、24 h及术后第3天VAS评分低于对照组,差异有统计学意义(P<0.05);胸腔镜组并发症发生率为4.34%,低于对照组的26.08%,差异有统计学意义(P<0.05)。结论胸腔镜根治术治疗早期肺癌效果满意,可缩短康复时间,降低术后痛感,且对机体免疫功能及肺功能影响小,安全性高。
Objective To analyze the effect of thoracoscopic surgery on the immune function of patients undergoing radical resection of early lung cancer.Methods A total of 92 patients with early lung cancer diagnosed and treated by the Department of Cardiothoracic Surgery of Xuancheng City Central Hospital from January 2018 to January 2021 were selected as the research objects.According to different surgical methods,they were divided into a thoracoscopy group and a control group,with 46 cases in each group.The control group underwent traditional thoracotomy,and the thoracoscopic group underwent thoracoscopic radical surgery.The perioperative indicators,immune function,lung function,VAS score and complications were compared between the two groups.Results The operation time,first time to get out of bed,and hospital stay in the thoracoscopy group were shorter than those in the control group.The postoperative drainage volume was less than that of the control group.The number of lymph node dissections was more than that of the control group,the difference was statistically significant(P<0.05);The IgG level of the thoracoscopy group was lower than that of the control group,and the levels of CD3^(+),CD4^(+)and NK were higher than those of the control group,the difference was statistically significant(P<0.05);The levels of FEV1 and MV in the thoracoscopy group were higher than those in the control group,the difference was statistically significant(P<0.05);The VAS score of the thoracoscopy group was lower than that of the control group at 1,12,24 h and the third day after surgery,the difference was statistically significant(P<0.05);The complication rate in the thoracoscopy group was 4.34%,which was lower than 26.08%in the control group,the difference was statistically significant(P<0.05).Conclusion Thoracoscopy is satisfactory in patients undergoing radical resection of early lung cancer.It can shorten the recovery time,reduce postoperative pain,and has little effect on the body's immune function and lung function,and has high safety.
作者
钱彬彬
王灿
QIAN Bin-bin;WANG Can(Department of Cardiothoracic Surgery,Xuancheng City Central Hospital,Xuancheng 242000,Anhui,China)
出处
《医学信息》
2021年第17期123-125,共3页
Journal of Medical Information
关键词
早期肺癌
胸腔镜手术
免疫功能
肺功能
Early lung cancer
Thoracoscopic surgery
Immune function
Lung function
