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银屑病患者P物质、神经生长因子水平与焦虑、抑郁的相关性研究 被引量:6

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摘要 银屑病是一种常见、易复发的慢性炎症性皮肤病,其发病机制目前尚不明确。国外的研究[1]表明银屑病是典型的心身疾病,心理因素如焦虑及抑郁等负性情绪可诱发或加重银屑病,有相当比例的银屑病是由精神紧张而触发或加重。近年来,有研究发现血清P物质(SP)和神经生长因子(NGF)可能是焦虑及抑郁情绪影响某些心身性皮肤病如银屑病病情活动程度的相关物质[2],但目前有关心理因素、SP及NGF与银屑病发病的报道国内很少见。本研究通过检测银屑病患者血清SP和NGF的水平,并对患者进行焦虑及抑郁的心理测试评估,探讨银屑病患者精神因素与血清中SP、NGF的相关性。
作者 刘丽萍
出处 《临床皮肤科杂志》 CAS CSCD 北大核心 2021年第8期473-474,共2页 Journal of Clinical Dermatology
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