摘要
目的分析吕梁市1起新型冠状病毒肺炎(COVID-19)家庭聚集性无症状感染者流行病学、临床特征以及肠道排毒情况。方法对吕梁市2020年2月26日出现的1起新型冠状病毒肺炎家庭聚集性无症状感染者进行随访,连续2个月对3例无症状感染者的咽拭子、肛拭子及血样本进行采样检测,收集研究对象的流行病史、临床表现以及诊疗情况进行分析。结果 3例无症状感染者与新型冠状病毒确诊病例有过接触史,均无临床症状,咽拭子核酸检测阴性后肛拭子多次检测为阳性,并且儿童肛拭子核酸阳性持续的时间较成人相对较长。在咽拭子阴性后感染者1检测到的肛拭子阳性持续时间为7 d,感染者2持续时间为12 d,感染者3持续时间为14 d。结论 COVID-19无症状感染者通过新型冠状病毒肺炎的密切接触者排查时发现,无临床症状;无症状感染者咽拭子新冠病毒核酸阴性后,肛拭子在一定时间内仍为阳性。
Objective To analyze the epidemiological and clinical characteristics and fecal viral shedding of a familial clustering epidemic asymptomatic infection cases caused by COVID-19 in Lvliang city. Methods A clustering epidemic asymptomatic infection cases caused by COVID-19 was followed up in Lvliang city on February 26,2020.The nasopharyngeal swabs, rectal swabs and blood samples of 3 asymptomatic patients were sampled and tested for 2 month in a row, and the epidemiological history, clinical manifestations and diagnosis and treatment of the subjects were collected and analyzed. Results The 3 cases with asymptomatic infection had a history of contact with the confirmed cases of COVID-19,all of them had no clinical symptoms, persistently tested positive on rectal swabs even after nasopharyngeal testing was negative and the positive duration of the positive rectal swab in children was longer than that in adults, the duration of infecter 1 was 7 days, infecter 2 was 12 days, infecter 3 was 14 days. Conclusion The COVID-19 asymptomatic infection cases infection was found by close contact screening and cluster epidemic investigation, without any clinical symptom;the nucleic acid of the COVID-19 in anal swab was still positive for a certain period of time after it was negative in the nasopharyngea swab of the asymptomatic infected person.
作者
张慧变
刘雅婷
程婷婷
陈冬
乔艳
武兴荣
ZHANG Hui-bian;LIU Ya-ting;CHENG Ting-ting;CHEN Dong;QIAO Yan;WU Xing-rong(Lvliang City Center for Disease Control and Prevention,Lvliang,Shanxi,033000,China;不详)
出处
《预防医学论坛》
2021年第3期224-226,共3页
Preventive Medicine Tribune
