摘要
目的观察高胆红素血症患儿分别采用颅脑CT、磁共振成像(MRI)技术检查,分析其脑损伤的诊断与评价结果。方法选择2019年2月至2020年4月我院收治的高胆红素血症患儿63例,为观察组;同期选择健康新生儿50例为对照组。分别测定两组新生儿神经测定评分(NBNA)、血清胆红素(TB)水平;并使用颅脑CT、MRI技术进行检查,分析不同检查方法扫描对患儿脑损伤评价结果,以脑干听觉诱发电位测定为金标准。结果观察组TB水平显著高于对照组,NBNA评分低于对照组,差异有统计学意义(P<0.05)。对比两种检查方法诊断结果,MRI诊断技术准确率、灵敏度均高于CT技术,差异有统计学意义(P<0.05)。头颅MRI阳性患儿3 d内高胆红素血症发生率为79.41%(27/34),高于头颅MRI阴性患儿17.24%(5/29),差异有统计学意义(P<0.05);阳性患儿NBNA评分为(32.50±1.36)分,低于阴性患儿(34.14±1.40)分,差异有统计学意义(P<0.05)。颅脑MRI技术的成本-效果比低于颅脑CT技术,MRI技术经济效益更高。结论相比于头颅CT技术,对高胆红素血症患儿运用MRI技术诊断准确度、灵敏度更高,联合NBNA评分,可作为早期评价患儿脑损伤的重要方法。
Objective To observe the diagnosis and evaluation of brain injury in children with hyperbilirubinemia by brain CT and magnetic resonance imaging(MRI).Methods A total of 63 children with hyperbilirubinemia treated in our hospital from February 2019 to April 2020 were selected as the observation group;50 healthy newborns in the same period were selected as the control group.The NBNA score and TB level were determined;the brain CT and MRI techniques were used and the evaluation results of brain injury in children with different methods were analyzed.The measurement of brainstem auditory evoked potential was the gold standard.Results The TB level in the observation group was significantly higher than that in the control group,while the NBNA score was lower(P<0.05).Comparing the diagnostic results of the two methods,the accuracy and sensitivity of MRI were higher than those of CT(P<0.05).The incidence of hyperbilirubinemia within 3 days in children with positive cranial MRI was 79.41%(27/34),which was higher than 17.24%(5/29)in children with negative cranial MRI(P<0.05);the NBNA score of positive children was(32.50±1.36),which was lower than that of negative children(34.14±1.40)(P<0.05).The cost-effectiveness ratio of brain MRI technology is lower than that of brain CT technology,and the economic benefit of MRI technology is higher.Conclusion Compared with cranial CT,MRI has higher accuracy and sensitivity in the diagnosis of hyperbilirubinemia in children,and combined with NBNA score,it can be used as an important method for early evaluation of brain injury in children.
作者
陈奕州
黄育鑫
马春浓
CHEN Yizhou;HUANG Yuxin;MA Chunnong(Puning People's Hospital,Jieyang 515300,China)
出处
《中国中西医结合儿科学》
2021年第4期340-343,共4页
Chinese Pediatrics of Integrated Traditional and Western Medicine
关键词
高胆红素血症
脑损伤
头颅CT
头颅磁共振成像
Hyperbilirubinemia
Brain injury
Cranial CT
Cranial magnetic resonance imaging
