摘要
目的探究舍曲林辅助治疗室性心律失常患者的效果及对负面情绪的影响。方法选取2017年6月~2019年10月期间90例室性心律失常患者,根据随机数字表法分组。对照组45例给予胺碘酮治疗,观察组45例增加舍曲林辅助治疗,2个月后,对比两组患者室性心律失常次数、心律变异性指标、焦虑抑郁情绪、睡眠质量及不良反应。结果治疗后观察组室性心律失常次数、HAMA、HAMD、PSQI评分低于对照组,SDNN、SDANN、RMSSD、PNN50均高于对照组,差异有统计学意义(P<0.05)。观察组不良反应发生率为8.89%高于对照组6.67%,差异无统计学意义(P>0.05)。结论舍曲林辅助治疗室性心律失常患者,可降低室性心律失常次数,促进心功能恢复,改善焦虑抑郁负面情绪,药物安全性高。
Objective To explore the effect of sertraline in adjuvant treatment of patients with ventricular arrhythmia and its influence on negative emotions. Methods From June 2017 to October 2019,90 patients with ventricular arrhythmia were selected and grouped according to the random number table method.45 patients in the control group were treated with amiodarone,and 45 patients in the observation group were treated with adjuvant sertraline. Two months later,the number of ventricular arrhythmia,heart rhythm variability indicators,anxiety and depression,sleep quality and adverse reactions were compared between the two groups. Results After treatment,the number of ventricular arrhythmias,HAMA,HAMD,and PSQI scores in the observation group were lower than those in the control group. SDNN,SDANN,RMSSD,and PNN50 were higher than those in the control group(P<0.05). The incidence of adverse reactions in the observation group was 8.89%,which was higher than that(6.67%)in the control group(P>0.05). Conclusion Sertraline adjuvant treatment of patients with ventricular arrhythmia can reduce the frequency of ventricular arrhythmia,promote heart function recovery,improve anxiety and depression and negative emotions with high safety.
作者
赵素贞
谢桥涛
牛方卿
丁红运
ZHAO Suzhen;XIE Qiaotao;NIU Fangqing(Department of Cardiovascular Medicine,Shaoling District People’s Hospital of Luohe City,Luohe 462000,China)
出处
《国际精神病学杂志》
2021年第4期700-702,710,共4页
Journal Of International Psychiatry
关键词
舍曲林
室性心律失常
负面情绪
Sertraline
Ventricular arrhythmia
Negative emotions
