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姑息治疗对晚期癌症患者癌性疼痛、食欲、睡眠质量及焦虑抑郁的影响 被引量:17

Effects of palliative treatment on cancer pain,appetite,sleep quality,anxiety and depression in patients with terminal cancer
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摘要 目的观察晚期癌症患者使用姑息治疗对癌性疼痛、食欲、睡眠质量及焦虑抑郁的影响。方法选择我院2016年5月~2018年5月收治的晚期癌症患者76例,随机分为观察组和对照组各38例,其中对照组给予常规干预,观察组在此基础上进行姑息治疗。观察治疗前后简化McGill疼痛问卷量表(SF-MPQ)评分、食欲及体重变化情况、匹兹堡睡眠质量指数问卷(PSQI)评分、汉密尔顿焦虑量表(HAMA)评分、汉密尔顿抑郁量表(HAMD)评分及癌症治疗功能评价系统-普适性量表(FACT-G)评分情况。结果观察组治疗后SF-MPQ评分改善情况均优于对照组(P<0.05);观察组治疗后食欲及体重变化情况均优于对照组(P<0.05);观察组治疗后PSQI量表、HAMA量表、AMD量表评分均低于对照组(P<0.05);观察组治疗后FACT-G量表各项评分均高于对照组(P<0.05)。结论晚期癌症患者使用姑息治疗能缓解癌性疼痛,改善食欲及体重变化情况,同时提高患者睡眠质量,减轻焦虑及抑郁评分,进而提高其生活质量。 Objective To observe the effects of palliative treatment on cancer pain,appetite,sleep quality,anxiety and depression in patients with terminal cancer. Methods 76 patients with terminal cancer who were admitted to the hospital from May 2016 to May 2018 were enrolled. They were randomly divided into observation group and control group,38 cases in each group. The control group was given routine intervention. On this basis,observation group was given palliative treatment. The score of Short-form McGill Pain Questionnaire(SF-MPQ),changes in appetite and body weight,scores of Pittsburgh Sleep Quality Index(PSQI),Hamilton Anxiety Scale(HAMA),Hamilton Depression Scale(HAMD)and Functional Assessment of Cancer Therapy-General(FACT-G)before and after treatment were observed. Results After treatment,improvement of SF-MPQ score in observation group was better than that in control group(P<0.05). After treatment,changes in appetite and body weight of observation group were better than those of control group(P<0.05). After treatment,scores of PSQI HAMA and HAMD in observation group were lower than those in control group(P<0.05),while scores of FACT-G were higher than those in control group(P<0.05). Conclusion The application of palliative treatment in patients with terminal cancer can alleviate cancer pain,improve appetite and body weight changes,improve their quality of sleep,reduce anxiety and depression scores,thus improving their quality of life.
作者 佟春雨 杨玲 TONG Chunyu;YANG Ling(The Third Clinical Medical College of Xinjiang Medical University,Urumqi 830011,China)
出处 《国际精神病学杂志》 2021年第4期718-722,共5页 Journal Of International Psychiatry
关键词 晚期癌症 姑息治疗 癌性疼痛 食欲 睡眠质量 焦虑抑郁情绪 Terminal cancer Palliative treatment Cancer pain Appetite Sleep quality Anxiety and depression
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