摘要
目的分析深圳某区0~36月龄儿童过敏性疾病症状的相关危险因素,为后期开展儿童过敏性疾病的干预提供理论依据。方法采用分层抽样的方法,于2020年7-12月,对到深圳某区社区健康服务机构开展儿童体检的0~36月龄儿童家长进行过敏性疾病的问卷调查,运用χ^(2)、t检验、二项Logistic回归进行统计分析,发现婴幼儿过敏性疾病症状的危险因素和保护因素。结果本次共收集调查对象399例,男性209例,女性190例,有过敏性疾病症状的病例组84例(21.05%);无过敏性疾病症状的对照组315例(78.95%)。单因素和多因素分析结果显示,母亲过敏史(OR=3.847,95%CI[1.483~9.976])、父亲过敏史(OR=3.394,95%CI[1.350~8.533])、家庭装修(OR=5.526,95%CI[1.181~25.857])、妊娠期疾病史(OR=2.819,95%CI[1.435~5.537])、出生1月内使用普通配方奶粉(OR=1.871,95%CI[1.081~3.237])是婴幼儿过敏性疾病症状的危险因素(P<0.05),而孕期补充益生菌(OR=0.402,95%CI[0.220-0.861])是婴幼儿过敏性疾病症状的保护因素(P<0.05)。结论母亲过敏史、父亲过敏史、家庭装修、妊娠期疾病史、出生1月内使用普通配方奶粉可能导致婴幼儿过敏性疾病症状的发生,而孕期补充益生菌有助于预防婴幼儿过敏性疾病症状的发生。
Objective In order to provide theoretical basis for the intervention of allergic disease,the related risk factors of allergic disease symptoms among children aged 0-36 months were analyzed in an area with large floating population in Shenzhen.Methods Stratified sampling method was performed to select 399 children aged 0-36 months and their mothers from a district in Shenzhen,a questionnaire survey was conducted to collect the data of allergic diseases.Chi square,t test and binomial logistic regression were used to analyze the data.The risk factors and protective factors of infant allergic diseases were analyzed.Results A total of 399 children were collected,including 209 males and 190 females.There were 84 cases(21.05%)in the case group with allergic disease symptoms,and 315 cases(78.95%)in the control group without allergic disease symptoms.Univariate and multivariate analysis showed that maternal allergic history(OR=3.847,95%CI[1.483-9.976]),father allergic history(OR=3.394,95%CI[1.350-8.533]),house decoration(OR=5.526,95%CI[1.181-25.857]),gestational disease history(OR=2.819,95%CI[1.435-5.537]),and use of common formula milk powder within one month of birth(OR=1.871,95%CI[1.081-3.237])were the risk factors of allergic disease symptoms in infants(P<0.05).While probiotics supplementation during pregnancy(OR=0.402,95%CI[0.220-0.861])was the protective factor of allergic disease symptoms in infants(P<0.05).Conclusion The factors of parents′allergic history,house decoration,gestational disease history,and use of common formula milk powder within one month of birth may lead to the occurrence of allergic disease symptoms,while probiotics supplementation during pregnancy can help to prevent the occurrence of allergic disease symptoms in infants.
作者
殷道根
何珍
曾小辉
段学燕
廖小兵
黄卫民
YIN Daogen;HE Zhen;ZENG Xiaohui;DUAN Xueyan;LIAO Xiaobing;HUANG Weimin(Regional Community Health Service Center of Shenzhen Longhua Guanlan sub-district/Kukeng Community Health Service Center of Shenzhen Longhua District Central Hospital,Guangdong Shenzhen 518110,China)
出处
《新疆医科大学学报》
CAS
2021年第9期1071-1076,共6页
Journal of Xinjiang Medical University
基金
广东省基础与应用基础研究基金项目(2020A1515010179)。
关键词
过敏性疾病症状
危险因素
保护因素
symptoms of allergic disease
risk factors
protective factors
