摘要
目的探讨慢性阻塞性肺疾病(COPD)并呼吸衰竭患者接受支气管镜联合无创正压通气(NPPV)治疗的临床效果。方法选取辽健集团铁煤总医院2018年7月至2020年11月收治的74例COPD并呼吸衰竭患者作为研究对象,按照随机数字表法分为对照组(37例)与观察组(37例)。对照组行NPPV治疗,观察组在对照组的基础上加用支气管镜治疗,比较两组的动脉血气指标[动脉血二氧化碳分压(PaCO_(2))、动脉血氧分压(PaO_(2))、酸碱度(pH)]、肺功能[肺总量(TLC)、第1秒用力呼气量(FEV_(1))/用力肺活量(FVC)、FVC]。结果两组治疗前的PaCO_(2)、PaO_(2)、pH、TLC、FEV_(1)/FVC、FVC水平比较,差异无统计学意义(P>0.05);观察组治疗2周后的PaCO_(2)水平低于对照组,且PaO_(2)、pH、TLC、FEV_(1)/FVC、FVC水平均高于对照组,差异有统计学意义(P<0.05)。结论对COPD并呼吸衰竭患者行支气管镜+NPPV治疗可以增强疗效,尽快改善患者血气指标与肺功能,值得推广。
Objective To investigate the clinical effect of patients with chronic obstructive pulmonary disease(COPD)and respiratory failure receiving bronchoscopy combined with non-invasive positive pressure ventilation(NPPV).Methods A total of 74 patients with COPD and respiratory failure admitted to the Iron Coal General Hospital of Liaojian Group from July 2018 to November 2020 were selected as the research objects,and they were divided into the control group(37 cases)and the observation group(37 cases)according to a random number table methods.The control group was treated with NPPV,and the observation group was treated with bronchoscope on the basis of the control group.The arterial blood gas indexes(arterial partial pressure of carbon dioxide[PaCO_(2)],arterial partial pressure of oxygen[PaO_(2)],pH),lung function(total lung capacity[TLC],forced expiratory volume in one second[FEV_(1)]/forced vital capacity[FVC],FVC)of the two groups were compared.Results There was no significant difference in the levels of PaCO_(2),PaO_(2),pH,TLC,FEV_(1)/FVC,FVC between the two groups before treatment(P>0.05).The level of PaCO_(2) of the observation group after 2 weeks of treatment was lower than that of the control group,and the levels of PaO_(2),pH,TLC,FEV_(1)/FVC,FVC of the observation group after 2 weeks of treatment were all higher than those of the control group,the differences were statistically significant(P<0.05).Conclusion Bronchoscope and NPPV in the treatment of patients with COPD and respiratory failure can enhance the efficacy,and improve the blood gas indicators and lung function of patients as soon as possible.It is worthy of promotion.
作者
张楠
ZHANG Nan(Department of Critical Care Medicine,Iron Coal General Hospital of Liaojian Group,Liaoning Province,Tieling 112700,China)
出处
《中国当代医药》
CAS
2021年第27期76-79,共4页
China Modern Medicine
关键词
支气管镜
无创正压通气
慢性阻塞性肺疾病
呼吸衰竭
临床效果
Bronchoscope
Non-invasive positive pressure ventilation
Chronic obstructive pulmonary disease
Respiratory failure
Clinical effects
