摘要
目的探讨急性肺疾病急性加重期(AECOPD)的临床特征,为临床诊治提供参考。方法于2020年3月,回顾性调查2018年新疆维吾尔自治区第三人民医院收治确诊为AECOPD的患者127例,患者均为男性,其中尘肺合并AECOPD患者作为合并组,共65例;单纯AECOPD患者作为对照组,共62例。调取患者住院病历,分析患者的临床特征、住院天数、费用的差异以及肺功能、血气分析的相关性。结果与对照组比较,合并组在年龄、身高、体重、体重指数(BMI)、族别、吸烟差异无统计学意义(P>0.05)。与对照组比较,合并组中性粒细胞百分比、超敏C反应蛋白(CRP)较高,氧分压较低,肺活量(VC)实测值、用力肺活量占预计值百分比(FVC/Pred%)、第一秒钟用力呼气容积实测值(FEV1)、第一秒用力呼气容积与预计值的百分比(FEV1/Pred%)较低,残气量占预计量百分比(RV/Pred%)、残气量与肺总量的比值(RV/TLC)较高,差异均有统计学意义(P<0.05)。合并组在住院时间及住院费用均高于对照组,差异有统计学意义(P<0.05)。结论尘肺合并AECOPD患者与单纯AECOPD患者相比较,感染炎症水平高、肺功能下降程度明显,住院时间更长及住院费用更高。
Objective To investigate the clinical characteristics of acute exacerbation of acute lung disease(AECOPD)and to provide reference for clinical diagnosis and treatment.Methods From January 2018 to December 2018,127 patients with AECOPD were investigated retrospectively in March 2020,including 65 cases of pneumoconiosis with AECOPD group,62 cases of AECOPD group,127 cases of AECOPD group,the clinical characteristics,length of stay,cost difference and the correlation between pulmonary function and blood gas were analyzed in patients with AECOPD.Results There was no significant difference in age,height,weight,BMI,ethnicity and smoking between the two groups(P>0.05).The percentage of Neutrophil and hs-crp in pneumoconiosis combined with AECOPD group were significantly higher than those in AECOPD group(P<0.05).The oxygen partial pressure in pneumoconiosis combined AECOPD group was lower than that in control group(P<0.05).VC,FVC/Pred%,FEV1/Pred%in pneumoconiosis combined with AECOPD group were lower than those in AECOPD group,RV/Pred%and RV/TLC were higher than those in AECOPD group(P<0.05).The hospitalization time and cost of the patients with AECOPD were significantly higher than that of the patients with AECOPD(P<0.05).Conclusion Compared with AECOPD group,the patients with pneumoconiosis combined AECOPD group had higher infection inflammation level,lower pulmonary function,longer hospitalization time and higher hospitalization cost.
作者
鄂文娟
加孜那·托哈依
侯婷婷
阿明古丽
E Wenjuan;Jiazina·Tuohayi;Hou Tingting;A mingguli(The Third People's Hospital of Xinjiang Uygur Autonomous Region,Urumqi 830011,China;The First Affiliated Hospital of Xinjiang Medical University,Urumqi 830011,China)
出处
《中华劳动卫生职业病杂志》
CAS
CSCD
北大核心
2021年第9期661-664,共4页
Chinese Journal of Industrial Hygiene and Occupational Diseases
关键词
尘肺
血气分析
肺功能
慢性阻塞性肺疾病
临床特征
Neumoconiosis
Blood gas analysis
Pulmonary function
Chronic obstructive pulmonary disease
Clinical features
