摘要
目的:探讨非营养性吸吮治疗早产儿胃肠道发育不良的临床效果及对生长发育的影响。方法:选取2019年1月-2020年9月本院收治的80例胃肠道发育不良早产儿,根据随机数字表法将患儿随机分成对照组和研究组,每组40例。对照组进行常规治疗,研究组进行非营养性吸吮治疗。比较两组患儿生长发育指标、喂养状况、并发症、SS与INS水平。结果:治疗1周,两组身长增长、体重、头围增长比较,差异均无统计学意义(P>0.05);治疗2周,研究组身长增长、体重、头围增长均高于对照组,差异均有统计学意义(P<0.05)。研究组胎便排尽时间、鼻饲管留置时间、胃肠道营养达标时间、出生体重恢复时间均短于对照组,反流次数少于对照组,差异均有统计学意义(P<0.05)。研究组喂养不耐受发生率低于对照组,差异有统计学意义(P<0.05)。治疗1周,两组SS、INS水平比较,差异均无统计学意义(P>0.05);治疗2周,研究组SS水平低于对照组,INS水平高于对照组,差异均有统计学意义(P<0.05)。治疗前,两组CRP、IgA、IgM、IgG比较,差异均无统计学意义(P>0.05);治疗后,研究组CRP低于对照组,IgA、IgM、IgG水平均高于对照组,差异均有统计学意义(P<0.05)。结论:胃肠道发育不良患儿经非营养性吸吮治疗,身长、体重、头围均增加,且缩短了胎便排尽、鼻饲管留置、胃肠道营养达标、出生体重恢复时间,降低了并发症发生率,提高了免疫功能,可维持正常生长抑素水平。因此,非营养性吸吮治疗值得在临床上广泛应用。
Objective:To investigate the clinical effect of non nutritive sucking on gastrointestinal dysplasia of premature infants and its influence on growth and development.Method:A total of 80 premature infants with gastrointestinal dysplasia treated in our hospital from January 2019 to September 2020 were selected,they were randomly divided into control group and study group according to the random number method,40 cases in each group.The control group received routine treatment and the study group received non nutritive sucking treatment.The growth and development indexes,feeding status,complications,SS and INS levels were compared between two groups.Result:After 1 week of treatment,there were no significant differences in body length growth,body weight and head circumference growth between two groups(P>0.05);after 2 weeks of treatment,body length growth,body weight and head circumference growth in the study group were higher than those in the control group,the differences were statistically significant(P<0.05).The time of fecal exhaust,indwelling time of nasal feeding tube,time of gastrointestinal nutrition up to standard,time of birth weight recovery in the study group were shorter than those in the control group,and the number of reflux was less than that in the control group,the differences were statistically significant(P<0.05).The incidence of feeding intolerance in study group was lower than that in control group,the difference was statistically significant(P<0.05).After 1 week of treatment,there were no significant differences in SS and INS between two groups(P>0.05);after 2 weeks of treatment,SS level in the study group was lower than that in the control group,while INS level in the study group was higher than that in the control group,the differences were statistically significant(P<0.05).Before treatment,there were no significant differences in CRP,IgA,IgM and IgG between two groups(P>0.05);after treatment,CRP in study group was lower than that in the control group,IgA,IgM and IgG levels were higher than those in the control group,the differences were statistically significant(P<0.05).Conclusion:After non nutritive sucking therapy,the length,weight and head circumference of children with gastrointestinal dysplasia are increased,and the time for fecal excretion,nasogastric feeding tube indwelling,gastrointestinal nutrition arrival and birth weight recovery time are shortened,the incidence of complications is reduced,immune function are increased,and the normal somatostatin level is maintained.Therefore,non nutritive sucking therapy is worthy of wide application in clinic.
作者
祝巍
臧大伟
ZHU Wei;ZANG Dawei(Jilin Women and Child Health Hospital,Changchun 130000,China)
出处
《中国医学创新》
CAS
2021年第28期33-37,共5页
Medical Innovation of China
基金
吉林省财政厅课题(2020J125)。
关键词
非营养性吸吮
早产儿
胃肠道发育不良
生长发育
Non nutritive sucking
Premature infant
Gastrointestinal dysplasia
Growth and development
