摘要
目的了解佛山市南海区变应性鼻炎患者(AR)变应原谱分布情况,为AR临床防治提供临床参考。方法选取2015年5月—2019年12月具有AR典型临床症状和体征的患者进行血清s IgE检测并分析其分布特征。结果1230例具备AR症状体征的患者中s IgE阳性率为99.19%,尘螨/粉螨(51.38%)是主要的变应原,其次为花生/大豆(45.04%)与蛋白/蛋黄(36.34%);未成年组在尘螨/粉螨、点青霉/交链孢霉/黑根霉、虾/蟹、猪肉/牛肉/羊肉、牛奶、蛋白/蛋黄、花生/大豆其变应原阳性率明显高于成年组,并且差异有统计学意义(P<0.05);男女与年龄之间变应原阳性率差异无统计学意义(P>0.05);80.65%患者具有混合过敏的情况,而未成年人混合过敏的比例要高于成年人。结论佛山市南海区变应原阳性率极高,尘螨/粉螨是诱发AR的主要变应原,是该地区防治的重点;未成年应尤其需注意食入性变应原与混合过敏的情况。
Objective To investigate the distribution of AR in Nanhai District of Foshan,and to provide clinical reference for the prevention and treatment of AR.Methods From May 2015 to December 2019,patients with typical clinical symptoms and signs of AR were selected to detect serum s Ig E and analyze its distribution characteristics.Results The positive rate of s Ig E was 99.19%in 1230 patients with AR symptoms and signs,followed by peanut/Soybean(45.04%)and protein/yolk(36.34%);the positive rate of s Ig E in the juvenile group was significant in dust mite/mite,Penicillium/Alternaria/Rhizopus,shrimp/crab,pork/beef/mutton,milk,protein/yolk,peanut/soybean.It was significantly higher than that of the adult group,and there was statistical difference(P<0.05).There was no significant difference in the positive rate of allergens between men and women and age(P>0.05).80.65% of patients had mixed allergy,while the proportion of mixed allergy of minors was higher than that of adults.Conclusion The positive rate of allergens is very high in Nanhai District of Foshan.Dust mite/acaroid mite is the main allergen that induces AR,which is the key point of prevention and control in this area.Juvenile should pay special attention to the situation of food allergen and mixed allergy.
作者
黄晓萍
孙珊
招敏娟
韦敬业
HUANG Xiaoping;SUN Shan;ZHAO Minjuan;WEI Jingye(Department of Otolaryngology,Nanhai District Public Health Hospital,Guangdong Province,Foshan 528226,China;Clinical Laboratory,Nanhai District Public Health Hospital,Guangdong Province,Foshan 528226,China)
出处
《光明中医》
2021年第19期3337-3340,共4页
GUANGMING JOURNAL OF CHINESE MEDICINE
关键词
变应性鼻炎
变应原
检测
allergicrhinitis
allergen
detection
