摘要
目的:探讨学龄前期儿童功能性便秘危险因素及其与中医证型的相关性。方法:选择2019年2月—2020年1月就诊的352例功能性便秘患儿作为观察组,选择同时期同年龄段360例健康儿童作为对照组,收集所纳入儿童资料,筛选功能性便秘危险因素;结合病史及四诊资料将功能性便秘患儿辨证分型,分析危险因素与中医证型之间的相关性。结果:多因素Logistic回归分析显示:母亲孕期喜甜食肉食及嗜辣、>6个月添加辅食、剖宫产、憋便、消化不良、饮水不足、母亲妊娠期糖尿病、排便不规律、抗生素使用>5次/年、恐惧排便、未进行排便训练、有家族便秘史等12项均为儿童功能性便秘危险因素(OR值分别为5.368、3.696、0.457、0.437、0.157、0.149、0.143、0.082、0.054、0.053、0.053、0.031,P<0.05);352例功能性便秘患儿常见中医证型频次由高到低依次为:食积便秘(29.5%)、燥热便秘(27.0%)、气虚便秘(21.6%)、气滞便秘(18.8%)、血虚便秘(3.1%);分析中医证型与危险因素相关性,按OR值大小排序分别为:食积便秘证与恐惧排便、排便不规律、饮水不足、母亲孕期喜肉食、消化不良、母亲妊娠期糖尿病有关;燥热便秘证与母亲孕期喜肉食、母亲孕期嗜辣、饮水不足、憋便有关;气虚便秘证与消化不良、饮水不足、母亲孕期喜肉食、排便不规律、滥用抗生素有关;气滞便秘证与母亲孕期喜甜食、饮水不足、家族史、滥用抗生素有关。结论:儿童功能性便秘的发生与多因素相关,且各中医证型与危险因素有一定的相关性。
Objective: To investigate the risk factors of functional constipation in preschool children and its correlation with Traditional Chinese Medicine(TCM) symptoms. Methods: A total of 352 children with functional constipation who visited our pediatric clinic from February 2019 to January 2020 were selected as the observation group, and 360 healthy children of the same age group at the same time were selected as the control group. The data of the included children were collected to screen the risk factors of functional constipation;the syndrome differentiation of the children with functional constipation was combined with the medical history and four diagnostic data to analyze the correlation between the risk factors and TCM symptoms. Results: Multivariate logistic regression analysis showed that 12 items such as maternal preference for sweets and meat and spicy during pregnancy, addition of complementary foods>6 months, cesarean section, holding stools, indigestion, insufficient drinking water, maternal gestational diabetes, irregular defecation, antibiotic use>5 times/year, fear of defecation, no defecation training, and a history of familial constipation were all risk factors for functional constipation in children;the common frequency of TCM symptoms in 352 children with functional constipation from high to low was: food constipation(29.5%), dryness and heat constipation(27.0%), Qi deficiency constipation(21.6%), Qi stagnation constipation(18.8%), and blood deficiency constipation(3.1%);the correlation between TCM symptoms and risk factors was analyzed according to the magnitude of OR, the food accumulation constipation syndrome was related to fear of defecation, irregular defecation, insufficient drinking water, maternal preference for meat during pregnancy, indigestion, and maternal gestational diabetes;the dryness and heat constipation syndrome was related to maternal preference for meat during pregnancy, maternal preference for spicy water during pregnancy, insufficient drinking water, and holding stools;the Qi deficiency constipation syndrome was related to indigestion, insufficient drinking water, maternal preference for meat during pregnancy, irregular defecation, and abuse of antibiotics;and the Qi stagnation constipation syndrome was related to maternal preference for sweets during pregnancy, insufficient drinking water, family history, and abuse of antibiotics. Conclusion: The occurrence of functional constipation in children is associated with multiple factors, and each TCM symptoms has a certain correlation with risk factors.
作者
夏瑞雪
牟春笋
XIA Ruixue;MOU Chunsun(Shandong University of Traditional Chinese Medicine,Jinan,250014,China;Department of Paediatrics,The Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine)
出处
《中国中西医结合消化杂志》
CAS
2021年第10期707-711,共5页
Chinese Journal of Integrated Traditional and Western Medicine on Digestion
基金
山东省中医药科技发展计划(No:2019-0226)。
关键词
儿童
功能性便秘
危险因素
中医证型
children
functional constipation
risk factors
Traditional Chinese Medicine symptoms
