摘要
目的 分析艾滋病病毒(HIV)抗体不确定结果特点,以及不确定人群的随访情况,对不确定结果增加认识并提出合理解决办法,为更好地管理HIV抗体不确定人群提供科学依据。方法 分析金山区疾病预防控制中心2014年-2019年的1 985份HIV抗体确证试验样本,并对其中275份不确定者进行分析,对抗体不确定结果人群进行随访。结果 HIV确证实验不确定者占比为13. 85%(275/1 985)。在HIV抗体不确定者中,以自愿咨询检测(VCT)、其他就诊者检测、术前检测居多。275例不确定结果中,复合带型出现频率高于单一带型,完成随访的52例患者,有gp160出现的复合带型阳转率为45. 16%(14/31),明显高于其他带型。不确定样本筛查S/CO值与是否转阳为相关因素。结论 应加强对抗体结果不确定人群的追踪随访,尤其对出现gp160带型的不确定者应尽早进行核酸检测,为及早确定感染状况提供实验依据。
Objective The characteristics of the uncertain results of HIV antibodies and the following—up of the uncertain population were analyzed to increase the understanding of the uncertain results and put forward reasonable solutions,so as to provide scientific basis for better management of the population with uncertain HIV antibodies.Methods A total of 1985 HIV antibody confirmator\,test samples collected from Jinshan District Center for Disease Control and Prevention from 2014 to 2019 were analyzed,and 275 unconfirmed HIV antibody confirmatory test samples were analyzed.Results A total of 13.85%(275/1985)of HIV confirmatory tests were not confirmed.Among those with uncertain HIV antibody,voluntary consultation test(VCT),other patients’test and preoperative test were the majority.Among the 275 cases with uncertain results,the frequency of compound banding was higher than that of single banding.Among the 52 patients who completed follow-up,the positive rate of compound banding with gpl60 was 45.16%(14/31),which was significantly higher than that of other banding.Uncertain sample screening S/CO value and whether positive or not is a related factor.Conclusion Follow-up should be strengthened for people with uncertain antibody results,especially for those with uncertain gpl60 bands,nucleic acid testing should be carried out as soon as possible to provide experimental basis for early determination of infection status.
作者
安洪海
袁佳春
吴洪彦
叶玉龙
杨志远
AN Hong-hai;YUAN Jia-chun;WU Hong-yan;YE Yu-long;YANG Zhi-yuan(Jinshan District Center for Disease Control and Prevention,Shanghai 201500,China)
出处
《中国卫生检验杂志》
CAS
2021年第21期2611-2613,2618,共4页
Chinese Journal of Health Laboratory Technology
基金
上海市金山区卫生和计划生育委员会科研课题(JSKJ-KTMS-2017-08)。
